Superpower vs Empirical Health
Complete Head-to-Head Comparison
Compare costs, biomarker coverage, and value to find the best blood testing service for your needs
Quick Comparison Summary
Best Value
Empirical Health
52.6 biomarkers per $100
Most Comprehensive
Tie
100+ biomarkers each
Most Tests Per Year
Superpower
2 tests/year
Cost & Value Comparison
Superpower
Annual Cost$349
Tests per Year2
Total Biomarkers100+
Cost per Test$174
Empirical Health
Annual Cost$190
Tests per Year1
Total Biomarkers100+
Cost per Test$190
Service Details
| Feature | Superpower | Empirical Health |
|---|---|---|
| Lab Locations | 2000+ labs nationwide | 2200+ locations |
| Key Features | Advanced lipid panel with LDL-P, inflammation ratios, fatty acid analysis, comprehensive autoimmune panel, concierge messaging | Personalized MD video visit included, doctor messaging, custom nutrition plan, exercise routines, mobile app |
| Notes | $349/year membership (about $0.96/day), per the superpower.com homepage checked 2026-09-23: two blood draws a year, a baseline of 100+ biomarkers and a retest 3-6 months later. Superpower markets this as 150+ biomarkers by counting both draws together; we list 100+, the baseline panel. The earlier $199 Baseline, $499 Performance and $999 Complete tiers no longer appear on the public site. Pricing may differ in New York and New Jersey. At-home collection costs extra. HSA/FSA eligible | $190 per test with MD video visit included. Single lab visit. HSA/FSA eligible |
Biomarker Coverage Comparison
56
Tests in Common
44
Only in Superpower
29
Only in Empirical Health
Tests Only in Superpower
- LDL Particle Number(Lipid Panel / Cardiovascular Health)
- LDL Particle Size(Lipid Panel / Cardiovascular Health)
- GGT (Gamma-Glutamyl Transferase)(Liver Function)
- Free T3 (Triiodothyronine)(Thyroid Function)
- TPO Antibodies (Thyroid Peroxidase)(Thyroid Function)
- Thyroglobulin Antibodies(Thyroid Function)
- T3 Uptake(Thyroid Function)
- Total T4(Thyroid Function)
- Total Testosterone(Sex Hormones (Male))
- Free Testosterone(Sex Hormones (Male))
- SHBG (Sex Hormone Binding Globulin)(Sex Hormones (Male))
- PSA (Prostate Specific Antigen)(Sex Hormones (Male))
32 more
- DHEA-S(Sex Hormones (Male))
- Estradiol (E2)(Sex Hormones (Female))
- Progesterone(Sex Hormones (Female))
- FSH (Follicle Stimulating Hormone)(Sex Hormones (Female))
- LH (Luteinizing Hormone)(Sex Hormones (Female))
- Prolactin(Sex Hormones (Female))
- AMH (Anti-Mullerian Hormone)(Sex Hormones (Female))
- ESR (Erythrocyte Sedimentation Rate)(Inflammation & Immune Markers)
- Homocysteine(Inflammation & Immune Markers)
- Cortisol(Stress & Adrenal Function)
- Omega-3 Index / Fatty Acids(Advanced / Specialty Markers)
- EPA (Eicosapentaenoic Acid)(Advanced / Specialty Markers)
- DHA (Docosahexaenoic Acid)(Advanced / Specialty Markers)
- Arachidonic Acid / EPA Ratio(Advanced / Specialty Markers)
- Heavy Metals - Mercury(Advanced / Specialty Markers)
- Creatine Kinase(Advanced / Specialty Markers)
- IGF-1 (Insulin-like Growth Factor)(Advanced / Specialty Markers)
- ANA Screen (Antinuclear Antibodies)(Autoimmune Markers)
- Rheumatoid Factor (RF)(Autoimmune Markers)
- Celiac Disease Panel (Comprehensive)(Autoimmune Markers)
- PSA Free (Prostate Cancer)(Cancer Screening Markers)
- Neutrophil/Lymphocyte Ratio(Additional Specialized Tests)
- Platelet/Lymphocyte Ratio(Additional Specialized Tests)
- Monocyte/HDL Ratio(Additional Specialized Tests)
- GGT/HDL Ratio(Additional Specialized Tests)
- Systemic Inflammation Index (SII)(Additional Specialized Tests)
- Free Androgen Index (FAI)(Additional Specialized Tests)
- Testosterone/Estradiol Ratio(Additional Specialized Tests)
- Cystatin C(Kidney Function)
- Phosphorus(Electrolytes & Minerals)
- Fructosamine(Metabolic Health / Glucose)
- Anion Gap(Electrolytes & Minerals)
Tests Only in Empirical Health
- Apolipoprotein A1 (ApoA1)(Lipid Panel / Cardiovascular Health)
- ApoB/ApoA1 Ratio(Lipid Panel / Cardiovascular Health)
- Urine Appearance(Urinalysis)
- Urine Color(Urinalysis)
- Urine pH(Urinalysis)
- Urine Specific Gravity(Urinalysis)
- Urine Protein(Urinalysis)
- Urine Glucose(Urinalysis)
- Urine Ketones(Urinalysis)
- Urine Bilirubin(Urinalysis)
- Urine Blood (Occult)(Urinalysis)
- Urine Nitrite(Urinalysis)
17 more
- Urine Leukocyte Esterase(Urinalysis)
- Urine WBC(Urinalysis)
- Urine RBC(Urinalysis)
- Urine Bacteria(Urinalysis)
- Squamous Epithelial Cells (Urine)(Urinalysis)
- Transitional Epithelial Cells (Urine)(Urinalysis)
- Renal Epithelial Cells (Urine)(Urinalysis)
- Hyaline Casts (Urine)(Urinalysis)
- Granular Casts (Urine)(Urinalysis)
- Urine Crystals(Urinalysis)
- Calcium Oxalate Crystals (Urine)(Urinalysis)
- Uric Acid Crystals (Urine)(Urinalysis)
- Triple Phosphate Crystals (Urine)(Urinalysis)
- Yeast (Urine)(Urinalysis)
- Band Neutrophils(Complete Blood Count (CBC))
- Reactive Lymphocytes(Complete Blood Count (CBC))
- Reducing Substances (Urine)(Urinalysis)
Full biomarker tableall 129 markers, side by side
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Based on this comparison, make an informed decision about your blood testing provider
Frequently Asked Questions
Which is cheaper, Superpower or Empirical Health?
Empirical Health is cheaper at $190/year, compared with $349/year for Superpower.
How much do Superpower and Empirical Health cost per year?
Superpower costs $349/year for 2 tests ($174 per test). Empirical Health costs $190/year for 1 test ($190 per test).
Which tests more biomarkers, Superpower or Empirical Health?
Both list 100+ biomarkers. Of the markers in our database, 56 are in both panels.
Which gives more biomarkers per dollar, Superpower or Empirical Health?
Empirical Health gives more biomarkers per dollar: 52.6 per $100 of annual cost, compared with 28.7 for Superpower. Count alone does not decide it; check whether the markers you need are included.
What does Superpower test that Empirical Health doesn't?
44 markers in our database are in Superpower's panel but not Empirical Health's, including LDL Particle Number, LDL Particle Size, GGT (Gamma-Glutamyl Transferase), and 41 more.
What does Empirical Health test that Superpower doesn't?
29 markers in our database are in Empirical Health's panel but not Superpower's, including Apolipoprotein A1 (ApoA1), ApoB/ApoA1 Ratio, Urine Appearance, and 26 more.
How many tests per year do Superpower and Empirical Health include?
Superpower includes 2 tests per year. Empirical Health includes 1 test per year.
Where do Superpower and Empirical Health draw blood?
Superpower: 2000+ labs nationwide. Empirical Health: 2200+ locations.
Can I use insurance with Superpower or Empirical Health?
Both are direct-to-consumer services paid out of pocket. Some buyers pay with HSA/FSA funds or submit receipts for out-of-network reimbursement; check with your plan and the provider.