Complete Testing & Optimization Guide
Optimal ranges, provider comparison, and strategies to improve your SHBG (Sex Hormone Binding Globulin) levels
Included in 6 of 10 major testing providers
Sex Hormones (Male)
regulating their bioavailability. Elevated in aging and hyperthyroidism;low in insulin resistance and obesity.
Abnormal SHBG (Sex Hormone Binding Globulin) levels can indicate underlying health issues that may go undetected without proper testing. Regular monitoring helps catch problems early when they're most treatable.
Understanding your SHBG (Sex Hormone Binding Globulin) levels enables targeted interventions, tracks treatment effectiveness, and helps optimize your overall health and performance.
Protein that binds sex hormones
Binds testosterone and estrogen
regulating their bioavailability. Elevated in aging and hyperthyroidism;low in insulin resistance and obesity.
| Provider | Includes Test | Annual Cost | Total Biomarkers |
|---|---|---|---|
 Superpower | ✓ | $199 | 100+ |
 WHOOP Advanced Labs | — | $349 | 65 |
 Labcorp OnDemand | — | $398 | 30+ |
| — | $486 | 40+ | |
| — | $468 | 83 | |
| ✓ | $798 | 100+ | |
 InsideTracker | ✓ | $680 | 48 |
 Function Health | ✓ | $499 | 100+ |
| ✓ | $900 | 70+ | |
| ✓ | $1150 | 110 | |
| — | $Varies | 75+ |
Choose from 6 providers that include this biomarker in their panels
SHBG (Sex Hormone Binding Globulin) is a sex hormones (male) biomarker that Protein that binds sex hormones The normal reference range is regulating their bioavailability. Elevated in aging and hyperthyroidism;low in insulin resistance and obesity.. Regular testing helps track changes and identify potential health issues early.
6 out of 10 major blood testing providers include SHBG (Sex Hormone Binding Globulin) in their standard panels. These include Superpower, Blueprint, Mito Health and others.
For most people, testing SHBG (Sex Hormone Binding Globulin) 2-4 times per year is recommended to establish baseline levels and track trends. If you have abnormal results or are actively working to optimize this biomarker, more frequent testing (quarterly) may be beneficial. Always consult with your healthcare provider for personalized testing frequency recommendations.
The standard laboratory reference range for SHBG (Sex Hormone Binding Globulin) is regulating their bioavailability. Elevated in aging and hyperthyroidism;low in insulin resistance and obesity.. However, many functional medicine practitioners recommend tighter "optimal" ranges for peak health and performance. Your ideal range may vary based on your age, sex, health goals, and other individual factors. Work with a healthcare provider familiar with optimal ranges to determine your target levels.
Most direct-to-consumer blood testing services that include SHBG (Sex Hormone Binding Globulin) provide the physician order as part of their service. However, some states have restrictions on direct-to-consumer testing. Check with your chosen provider about availability in your state and whether they provide the necessary physician authorization.
Binds testosterone and estrogen
This information is for educational purposes only and is not medical advice. Always consult with a qualified healthcare provider about your specific health needs and before making decisions about blood testing.
