TRT & Hormone Optimization Clinics 2026
Compare TRT and hormone optimization clinics. Pricing, medications, lab work, and provider support compared.
Pricing & Plans Comparison
Complete cost breakdown including monthly fees, lab work, and medications. Prices verified Aug 2026
| Provider | Monthly Cost | Annual Cost | Labs Included | Prescriber Type | State Availability |
|---|---|---|---|---|---|
| No monthly fee | $299 one-time | No - billed separately at member rates | MD/DO | 46 states (not NY, NJ, RI, HI or territories) | |
| $250/mo | $3000/yr | Basic hormone panel | MD/DO | All 50 states via telemedicine | |
| $99/mo | $1188/yr | Basic hormone panel | NP/PA | 45 states | |
| $155/mo | $1860/yr | Comprehensive panel (50+ biomarkers) | MD/DO | 47 states | |
| $199/mo | $2388/yr | Basic hormone panel | MD (Urologist) | 20 states | |
| $79/mo | $948/yr | Comprehensive hormone panel | MD | 48 states (not AL or ID) | |
| $99.99/mo | $1200/yr | No - sold separately | Physician | Most US states | |
| $129/mo | $1548/yr | Yes | Licensed provider | Most US states |
Medications & Treatments
Compare available medications, pharmacy options, and additional treatments offered by each provider.
| Provider | Medications Offered | Pharmacy Type | Injection Training | Patient Portal |
|---|---|---|---|---|
| Marek Health | Testosterone, HCG, AI, Nandrolone, Oxandrolone | In-house compounding | Yes | Yes |
| Defy Medical | Testosterone, HCG, AI, Clomid | Partner pharmacies | Yes | Yes |
| TRT Nation | Testosterone cypionate, HCG, AI | Partner pharmacies | Yes | Yes |
| Hone Health | Testosterone (injections/cream/troches), Clomiphene, Enclomiphene, Anastrozole | Partner pharmacies | Yes | Yes |
| Fountain TRT | Testosterone cream | Partner pharmacies | No | Yes |
| PeterMD | Testosterone, HCG, AI, Peptides, GH | In-house compounding | Yes | Yes |
| Maximus | Enclomiphene, Oral testosterone, Testosterone cream, GLP-1 | Partner pharmacy | No | Yes |
| Henry Meds | Testosterone injections, Testosterone cream, KYZATREX oral | Partner pharmacy | Yes | Yes |
Provider Details
In-depth look at each TRT clinic including features, pricing, and who it's best for.
Marek Health
Key Features
One-time lifetime membership fee, no recurring charge, coaching and clinician consults, custom lab report and protocol, member-discounted labs and pharmacy
Details
Guided Optimization is a $299 ONE-TIME fee granting lifetime access - Marek charges no recurring membership. Labs, supplements and prescriptions are billed separately at member-discounted rates, not bundled. Lab panels are sold through marekdiagnostics.com: Base $250, Total Health Comprehensive $495, Complete $895, Executive $1,950. Note marekhealth.com is IP-geo-blocked to automated tools; marekdiagnostics.com is the working commerce backend.
Defy Medical
Key Features
Operating since 2013, flexible protocols, no subscription/contract
Details
Defy charges no monthly fee - services are paid for at the time of purchase, with no subscription or contract. The figures here are modelled from Defy's own published averages: under $250/month in year one and under $200/month thereafter, inclusive of medications, lab work and consultations. Actual cost varies with deficiency severity, dosage, delivery system and auxiliary medications.
TRT Nation
Key Features
$99/month all-inclusive, unlimited doctor access, supplies and shipping included
Details
$99/month includes testosterone cypionate, injection supplies, shipping, and unlimited doctor consultations. Lab work: patients can supply outside labs or run through clinic ($129 lab fee). Blood work required after first 10 weeks, then 6 months, then annually. HSA/FSA eligible. NOTE: trtnation.com blocks automated verification at IP level (Cloudflare), so these figures could not be re-confirmed in the August 2026 refresh and may be stale.
Hone Health
Key Features
At-home testing option, 40+ biomarkers, retesting every 90 days on Premium, 5-day consult and 10-day med delivery
Details
Two memberships: Premium $155/mo (regular lab testing, physician consults, full medication access) and Basic $25/mo (labs every 6 months, consults a la carte, member pricing on medications). No commitment, cancel anytime. The former Plus tier at $129/mo no longer appears. Medications are billed separately: testosterone cream $60/mo, troches $60/mo, enclomiphene $42/mo, clomiphene $38/mo. Initial biomarker test $65 (list $165), 50+ biomarkers, at-home or 2,000+ lab locations.
Fountain TRT
Key Features
All-inclusive testosterone cream (no injections), led by board-certified urologists, telehealth consults
Details
$199/month all-inclusive - medication, video visits and ongoing medical support, no hidden fees, cancel anytime. Follow-ups every 3-6 months. Topical cream applied daily to the shoulder, no injections. Founded and led by Dr Doron Stember, a board-certified urologist. Available in 20 states only: AL, AZ, CA, CO, CT, FL, GA, IL, IN, MI, NJ, NY, NC, OH, PA, TN, TX, VA, WA, WI.
Key Features
Now PeterMD, tiered pricing, advanced protocols, peptide options
Details
Rebranded from Peter Uncaged MD to PeterMD. Three plans: $79/mo on a 12-month prepay ($948 total, the rate shown here), $109/mo on 6-month prepay ($654), or $139/mo month-to-month. Includes testosterone cypionate up to 200mg weekly, an aromatase inhibitor if needed, supplies, shipping and all physician consults. Labs are separate: Step 1 Labs $95 for new patients, follow-up labs $124.50, comprehensive panel $297. Not available in Alabama or Idaho.
Key Features
Enclomiphene-first non-injectable approach, CLIA at-home labs included, fertility-friendly protocols, results in under 48 hours
Details
EP-02 enclomiphene protocol: $99.99/mo on a 12-month plan (the rate shown here), $149.99/mo quarterly, or $199.99/mo month-to-month. New clients on the 12-month plan get 50% off month one. IMPORTANT CORRECTION: labs are NOT included. Maximus defines the bundle as medication, doctor consultations, ongoing monitoring and 24/7 care-team messaging - labs are absent from that list and sold separately: an at-home testosterone test is $99.99 each, and comprehensive panels are $199.99/yr (Optimal) or $349.99/yr (Maximal). Note the collision: the at-home test costs $99.99 ONCE while the enclomiphene plan costs $99.99 per MONTH. Full protocol range is $99.99-$199.99/mo. Enclomiphene-first, non-injectable, fertility-preserving.
Henry Meds
Key Features
Flat monthly price including medication, supplies and follow-up labs, aromatase inhibitor at no extra cost when appropriate, no insurance required
Details
$129/month starting price for testosterone injections or cream; $179/month for KYZATREX oral (not available in California). Verified all-inclusive: Henry states medication and supplies are included, an aromatase inhibitor is prescribed at no extra cost where appropriate, and labs are included as well, with one monthly payment covering the provider visit, medication, supplies and ongoing care. No hidden fees, no long-term contracts, cancel anytime - and no cheaper committed tier exists, so month-to-month is the best available rate. Note shipments arrive every 45 days for injectables and every 90 days for oral tablets, but billing is monthly.
Important Considerations
- Medical supervision required: TRT requires ongoing blood work and physician monitoring
- Fertility impact: Exogenous testosterone can affect sperm production - discuss with your provider
- Not for everyone: TRT is not appropriate for those with prostate cancer, severe sleep apnea, or certain cardiovascular conditions
- Commitment: TRT is typically a long-term or lifelong therapy - understand the commitment before starting
Frequently Asked Questions
What is TRT and who needs it?
Testosterone Replacement Therapy (TRT) is a medical treatment for men with clinically low testosterone levels (hypogonadism). Symptoms can include fatigue, low libido, depression, difficulty building muscle, and cognitive issues. TRT is typically recommended when blood tests confirm low testosterone and symptoms are present.
How much does TRT cost per month?
Among the 8 clinics compared here, monthly fees run from $79 (PeterMD) to $250 (Defy Medical). Marek Health charges no monthly fee: $299 one time, with labs and prescriptions billed separately. What the fee covers varies: some clinics include medication and labs, others bill them separately, and the lowest rates often require a prepaid plan. HSA/FSA funds can often be used.
Can I get TRT online?
Yes, all providers listed here offer telemedicine consultations. You'll complete blood work at a local lab, have a video consultation with a licensed provider, and receive medications shipped to your door. Most services operate in 40+ states.
What medications are typically prescribed?
Common TRT medications include testosterone cypionate or enanthate (injectable), HCG (to maintain fertility and testicular function), aromatase inhibitors (to control estrogen), and sometimes clomiphene (an alternative to testosterone). Some clinics also offer peptides and growth hormone protocols.
How often do I need blood work?
Most providers require blood work every 3-6 months to monitor testosterone levels, hematocrit, PSA, estradiol, and other markers. Many clinics include labs in their monthly fee, while others charge separately.
Is TRT covered by insurance?
Some insurance plans cover TRT if you have a diagnosis of hypogonadism. However, most online TRT clinics operate on a cash-pay model. HSA/FSA funds are typically eligible for TRT expenses.
What testosterone levels qualify for TRT?
Most clinics consider total testosterone below 300 ng/dL as low, though symptoms matter more than numbers alone. Some men experience low-T symptoms at 400-500 ng/dL, while others feel fine at 300. Free testosterone, SHBG, and symptoms are also considered. Online TRT clinics may have different thresholds than traditional endocrinologists.
Will TRT affect my fertility?
Yes, exogenous testosterone suppresses natural testosterone production and can significantly reduce sperm count, potentially causing temporary infertility. HCG is often prescribed alongside testosterone to maintain testicular function and fertility. If preserving fertility is important, discuss this with your provider before starting - alternatives like clomiphene may be recommended instead.
How long does it take to see results from TRT?
Timeline varies by symptom: libido and energy often improve within 3-6 weeks, mood and cognitive benefits appear around 6-12 weeks, body composition changes (muscle gain, fat loss) take 3-6 months, and maximum benefits are typically seen at 12+ months. Optimal dosing may require several adjustments based on blood work and symptom response.
What are the potential side effects of TRT?
Common side effects include acne, increased hematocrit (thickened blood), water retention, and testicular shrinkage. Elevated estrogen can cause gynecomastia (breast tissue growth) - managed with aromatase inhibitors. More serious risks include sleep apnea worsening, cardiovascular concerns in some populations, and fertility suppression. Regular blood work monitors these issues.
Monitor Your Hormone Optimization
Track your TRT progress with comprehensive blood testing to ensure optimal levels and safety.
Compare Blood Test ServicesImportant Disclaimer
This comparison is for informational purposes only and is not medical advice. TRT is a prescription medication that requires physician oversight. Prices were last checked against each provider's own site (Apr 2026 to Aug 2026) and may have changed since. Always consult with a healthcare provider before starting any hormone therapy.