Superpower vs Blueprint

Complete Head-to-Head Comparison

Compare costs, biomarker coverage, and value to find the best blood testing service for your needs

Superpower
Blueprint
✓ Independent Analysis✓ Prices verified Aug 2026✓ Complete Biomarker Coverage

Quick Comparison Summary

Best Value
Superpower
28.7 biomarkers per $100
Most Comprehensive
Tie
100+ biomarkers each
Most Tests Per Year
Tie
2 tests/year each

Cost & Value Comparison

Service Details

FeatureSuperpowerBlueprint
Lab Locations2000+ labs nationwideLabcorp (3500+)
Key FeaturesAdvanced lipid panel with LDL-P, inflammation ratios, fatty acid analysis, comprehensive autoimmune panel, concierge messagingBryan Johnson protocol, Don't Die app results, personalized longevity protocols
Notes$349/year membership (about $0.96/day), per the superpower.com homepage checked 2026-09-23: two blood draws a year, a baseline of 100+ biomarkers and a retest 3-6 months later. Superpower markets this as 150+ biomarkers by counting both draws together; we list 100+, the baseline panel. The earlier $199 Baseline, $499 Performance and $999 Complete tiers no longer appear on the public site. Pricing may differ in New York and New Jersey. At-home collection costs extra. HSA/FSA eligibleRestructured to a $365/year Biomarkers membership ($1/day, billed annually): two blood panels plus urine per year - a baseline of up to 140 biomarkers and a 6-month follow-up of up to 86, marketed as 100+ biomarkers and 160+ measurements per year. Labcorp partnership, 3,500+ US draw locations. One-time panels still sold separately: Basic $375 (67 biomarkers), Advanced $575 (108 biomarkers). Speed of Aging epigenetic test $325 and Microplastics test $135 are separate and not bundled. HSA/FSA eligible.

Biomarker Coverage Comparison

74
Tests in Common
26
Only in Superpower
42
Only in Blueprint

Tests Only in Superpower

14 more

Tests Only in Blueprint

30 more
Full biomarker tableall 142 markers, side by side

Filter by Category

BiomarkerSuperpowerBlueprint
Complete Blood Count (CBC)
Hemoglobin✓✓
ABO Blood Type—✓
Hematocrit✓✓
Red Blood Cell Count (RBC)✓✓
White Blood Cell Count (WBC)✓✓
Platelet Count✓✓
MCV, MCH, MCHC✓✓
RDW (Red Cell Distribution Width)✓✓
Mean Platelet Volume (MPV)✓✓
Neutrophils✓✓
Lymphocytes✓✓
Monocytes✓✓
Eosinophils✓✓
Basophils✓✓
Lipid Panel / Cardiovascular Health
Total Cholesterol✓✓
LDL Cholesterol✓✓
HDL Cholesterol✓✓
Triglycerides✓✓
VLDL Cholesterol✓✓
Apolipoprotein B (ApoB)✓✓
Lipoprotein (a)✓✓
LDL Particle Number✓—
LDL Particle Size✓—
Non-HDL Cholesterol✓✓
Total Cholesterol/HDL Ratio✓—
LDL/HDL Ratio✓—
LDL Small—✓
LDL Medium—✓
LDL Pattern—✓
LDL Peak Size—✓
Omega-6/Omega-3 Ratio—✓
Metabolic Health / Glucose
Fasting Glucose✓✓
Hemoglobin A1c (HbA1c)✓✓
Insulin✓✓
Uric Acid✓✓
Fructosamine✓—
Liver Function
ALT (Alanine Aminotransferase)✓✓
AST (Aspartate Aminotransferase)✓✓
ALP (Alkaline Phosphatase)✓✓
GGT (Gamma-Glutamyl Transferase)✓✓
Bilirubin (Total)✓✓
Albumin✓✓
Total Protein✓✓
Globulin✓✓
Lipase—✓
De Ritis Ratio (AST/ALT)✓—
Kidney Function
Creatinine✓✓
BUN (Blood Urea Nitrogen)✓✓
eGFR (Estimated Glomerular Filtration Rate)✓✓
BUN/Creatinine Ratio✓✓
Cystatin C✓—
Albumin/Globulin Ratio (A/G)✓—
Electrolytes & Minerals
Sodium✓✓
Potassium✓✓
Chloride✓✓
Carbon Dioxide (CO2)✓✓
Calcium✓✓
Magnesium✓✓
Zinc—✓
Phosphorus✓—
Anion Gap✓—
Thyroid Function
TSH (Thyroid Stimulating Hormone)✓✓
Free T4 (Thyroxine)✓✓
Free T3 (Triiodothyronine)✓✓
TPO Antibodies (Thyroid Peroxidase)✓—
Thyroglobulin Antibodies✓—
T3 Uptake✓—
Total T4✓✓
Sex Hormones (Male)
Total Testosterone✓✓
Free Testosterone✓✓
SHBG (Sex Hormone Binding Globulin)✓✓
PSA (Prostate Specific Antigen)✓✓
DHEA-S✓✓
Sex Hormones (Female)
Estradiol (E2)✓✓
Progesterone✓✓
FSH (Follicle Stimulating Hormone)✓✓
LH (Luteinizing Hormone)✓✓
Prolactin✓✓
AMH (Anti-Mullerian Hormone)✓—
Inflammation & Immune Markers
hs-CRP (High Sensitivity C-Reactive Protein)✓✓
ESR (Erythrocyte Sedimentation Rate)✓—
Homocysteine✓✓
Vitamins & Nutrients
Vitamin D (25-Hydroxy)✓✓
Vitamin B12✓✓
Folate✓✓
Ferritin✓✓
Iron (Serum)✓✓
TIBC (Total Iron Binding Capacity)✓✓
Stress & Adrenal Function
Cortisol✓✓
Advanced / Specialty Markers
Omega-3 Index / Fatty Acids✓✓
EPA (Eicosapentaenoic Acid)✓—
DHA (Docosahexaenoic Acid)✓—
Arachidonic Acid / EPA Ratio✓✓
Heavy Metals - Lead—✓
Heavy Metals - Mercury✓✓
Creatine Kinase✓—
IGF-1 (Insulin-like Growth Factor)✓✓
Leptin—✓
Omega-6 Total—✓
Linoleic Acid—✓
Arachidonic Acid—✓
Autoimmune Markers
ANA Screen (Antinuclear Antibodies)✓✓
ANA Titer—✓
ANA Pattern—✓
Rheumatoid Factor (RF)✓✓
Celiac Disease Panel (Comprehensive)✓—
Cancer Screening Markers
PSA Free (Prostate Cancer)✓✓
Additional Specialized Tests
Neutrophil/Lymphocyte Ratio✓—
Platelet/Lymphocyte Ratio✓—
Monocyte/HDL Ratio✓—
Transferrin Saturation✓✓
GGT/HDL Ratio✓—
Systemic Inflammation Index (SII)✓—
Free Androgen Index (FAI)✓—
Testosterone/Estradiol Ratio✓—
Urinalysis
Urine Appearance—✓
Urine Albumin—✓
Urine Color—✓
Urine pH—✓
Urine Specific Gravity—✓
Urine Protein—✓
Urine Glucose—✓
Urine Ketones—✓
Urine Bilirubin—✓
Urine Blood (Occult)—✓
Urine Nitrite—✓
Urine Leukocyte Esterase—✓
Urine WBC—✓
Urine RBC—✓
Urine Bacteria—✓
Squamous Epithelial Cells (Urine)—✓
Transitional Epithelial Cells (Urine)—✓
Renal Epithelial Cells (Urine)—✓
Hyaline Casts (Urine)—✓
Granular Casts (Urine)—✓
Urine Crystals—✓
Calcium Oxalate Crystals (Urine)—✓
Uric Acid Crystals (Urine)—✓
Triple Phosphate Crystals (Urine)—✓
Yeast (Urine)—✓
Reducing Substances (Urine)—✓
Pancreas & Digestive
Amylase—✓

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Based on this comparison, make an informed decision about your blood testing provider

Frequently Asked Questions

Which is cheaper, Superpower or Blueprint?
Superpower is cheaper at $349/year, compared with $365/year for Blueprint.
How much do Superpower and Blueprint cost per year?
Superpower costs $349/year for 2 tests ($174 per test). Blueprint costs $365/year for 2 tests ($182 per test).
Which tests more biomarkers, Superpower or Blueprint?
Both list 100+ biomarkers. Of the markers in our database, 74 are in both panels.
Which gives more biomarkers per dollar, Superpower or Blueprint?
Superpower gives more biomarkers per dollar: 28.7 per $100 of annual cost, compared with 27.4 for Blueprint. Count alone does not decide it; check whether the markers you need are included.
What does Superpower test that Blueprint doesn't?
26 markers in our database are in Superpower's panel but not Blueprint's, including LDL Particle Number, LDL Particle Size, TPO Antibodies (Thyroid Peroxidase), and 23 more.
What does Blueprint test that Superpower doesn't?
42 markers in our database are in Blueprint's panel but not Superpower's, including ABO Blood Type, Heavy Metals - Lead, ANA Titer, and 39 more.
How many tests per year do Superpower and Blueprint include?
Superpower includes 2 tests per year. Blueprint includes 2 tests per year.
Where do Superpower and Blueprint draw blood?
Superpower: 2000+ labs nationwide. Blueprint: Labcorp (3500+).
Can I use insurance with Superpower or Blueprint?
Both are direct-to-consumer services paid out of pocket. Some buyers pay with HSA/FSA funds or submit receipts for out-of-network reimbursement; check with your plan and the provider.

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