Blueprint vs SiPhox Health
Complete Head-to-Head Comparison
Compare costs, biomarker coverage, and value to find the best blood testing service for your needs
Blueprint
Quick Comparison Summary
Best Value
Blueprint
27.4 biomarkers per $100
Most Comprehensive
Blueprint
100+ biomarkers tested
Most Tests Per Year
SiPhox Health
4 tests/year
Cost & Value Comparison
Blueprint
Annual Cost$365
Tests per Year2
Total Biomarkers100+
Cost per Test$182
SiPhox Health
Annual Cost$996
Tests per Year4
Total Biomarkers59
Cost per Test$249
Service Details
| Feature | Blueprint | SiPhox Health |
|---|---|---|
| Lab Locations | Labcorp (3500+) | At-home |
| Key Features | Bryan Johnson protocol, Don't Die app results, personalized longevity protocols | Needle-free EasyDraw device, AI longevity expert (Sai), wearable integrations (Oura/Fitbit/Apple Watch), supplement recommendations, third-party lab uploads |
| Notes | Restructured to a $365/year Biomarkers membership ($1/day, billed annually): two blood panels plus urine per year - a baseline of up to 140 biomarkers and a 6-month follow-up of up to 86, marketed as 100+ biomarkers and 160+ measurements per year. Labcorp partnership, 3,500+ US draw locations. One-time panels still sold separately: Basic $375 (67 biomarkers), Advanced $575 (108 biomarkers). Speed of Aging epigenetic test $325 and Microplastics test $135 are separate and not bundled. HSA/FSA eligible. | Priced here as the Ultimate 360 panel, the SKU the 59-biomarker count describes: membership $124 per test cycle plus the Ultimate 360 upgrade at +$125 per cycle, 4 quarterly cycles = $996/yr plus shipping. Membership alone is $124/cycle ($496/yr quarterly) and includes four switchable core panels: Longevity Essentials (25 biomarkers), Thyroid Focus, Hormone Focus, Heart & Metabolic. GLP Monitoring Panel +$75/cycle. At-home needle-free EasyDraw collection. Our 20% affiliate code applies to the first billing cycle only, membership only, excluding shipping and upgrades. HSA/FSA eligible. |
Biomarker Coverage Comparison
43
Tests in Common
73
Only in Blueprint
4
Only in SiPhox Health
Tests Only in Blueprint
- ABO Blood Type(Complete Blood Count (CBC))
- Hematocrit(Complete Blood Count (CBC))
- Red Blood Cell Count (RBC)(Complete Blood Count (CBC))
- White Blood Cell Count (WBC)(Complete Blood Count (CBC))
- Platelet Count(Complete Blood Count (CBC))
- MCV, MCH, MCHC(Complete Blood Count (CBC))
- RDW (Red Cell Distribution Width)(Complete Blood Count (CBC))
- Fasting Glucose(Metabolic Health / Glucose)
- Insulin(Metabolic Health / Glucose)
- Uric Acid(Metabolic Health / Glucose)
- GGT (Gamma-Glutamyl Transferase)(Liver Function)
- Sodium(Electrolytes & Minerals)
61 more
- Potassium(Electrolytes & Minerals)
- Chloride(Electrolytes & Minerals)
- Carbon Dioxide (CO2)(Electrolytes & Minerals)
- Magnesium(Electrolytes & Minerals)
- Total T4(Thyroid Function)
- TIBC (Total Iron Binding Capacity)(Vitamins & Nutrients)
- Omega-3 Index / Fatty Acids(Advanced / Specialty Markers)
- Arachidonic Acid / EPA Ratio(Advanced / Specialty Markers)
- Heavy Metals - Lead(Advanced / Specialty Markers)
- Heavy Metals - Mercury(Advanced / Specialty Markers)
- IGF-1 (Insulin-like Growth Factor)(Advanced / Specialty Markers)
- ANA Screen (Antinuclear Antibodies)(Autoimmune Markers)
- ANA Titer(Autoimmune Markers)
- ANA Pattern(Autoimmune Markers)
- Rheumatoid Factor (RF)(Autoimmune Markers)
- PSA Free (Prostate Cancer)(Cancer Screening Markers)
- Mean Platelet Volume (MPV)(Complete Blood Count (CBC))
- Zinc(Electrolytes & Minerals)
- Lipase(Liver Function)
- Leptin(Advanced / Specialty Markers)
- Omega-6 Total(Advanced / Specialty Markers)
- Linoleic Acid(Advanced / Specialty Markers)
- Arachidonic Acid(Advanced / Specialty Markers)
- Neutrophils(Complete Blood Count (CBC))
- Lymphocytes(Complete Blood Count (CBC))
- Monocytes(Complete Blood Count (CBC))
- Eosinophils(Complete Blood Count (CBC))
- Basophils(Complete Blood Count (CBC))
- Non-HDL Cholesterol(Lipid Panel / Cardiovascular Health)
- Urine Appearance(Urinalysis)
- Urine Albumin(Urinalysis)
- Urine Color(Urinalysis)
- Urine pH(Urinalysis)
- Urine Specific Gravity(Urinalysis)
- Urine Protein(Urinalysis)
- Urine Glucose(Urinalysis)
- Urine Ketones(Urinalysis)
- Urine Bilirubin(Urinalysis)
- Urine Blood (Occult)(Urinalysis)
- Urine Nitrite(Urinalysis)
- Urine Leukocyte Esterase(Urinalysis)
- Urine WBC(Urinalysis)
- Urine RBC(Urinalysis)
- Urine Bacteria(Urinalysis)
- Squamous Epithelial Cells (Urine)(Urinalysis)
- Transitional Epithelial Cells (Urine)(Urinalysis)
- Renal Epithelial Cells (Urine)(Urinalysis)
- Hyaline Casts (Urine)(Urinalysis)
- Granular Casts (Urine)(Urinalysis)
- Urine Crystals(Urinalysis)
- Calcium Oxalate Crystals (Urine)(Urinalysis)
- Uric Acid Crystals (Urine)(Urinalysis)
- Triple Phosphate Crystals (Urine)(Urinalysis)
- Yeast (Urine)(Urinalysis)
- Reducing Substances (Urine)(Urinalysis)
- LDL Small(Lipid Panel / Cardiovascular Health)
- LDL Medium(Lipid Panel / Cardiovascular Health)
- LDL Pattern(Lipid Panel / Cardiovascular Health)
- LDL Peak Size(Lipid Panel / Cardiovascular Health)
- Omega-6/Omega-3 Ratio(Lipid Panel / Cardiovascular Health)
- Amylase(Pancreas & Digestive)
Tests Only in SiPhox Health
- TPO Antibodies (Thyroid Peroxidase)(Thyroid Function)
- Thyroglobulin Antibodies(Thyroid Function)
- AMH (Anti-Mullerian Hormone)(Sex Hormones (Female))
- Free Androgen Index (FAI)(Additional Specialized Tests)
Full biomarker tableall 120 markers, side by side
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Frequently Asked Questions
Which is cheaper, Blueprint or SiPhox Health?
Blueprint is cheaper at $365/year, compared with $996/year for SiPhox Health.
How much do Blueprint and SiPhox Health cost per year?
Blueprint costs $365/year for 2 tests ($182 per test). SiPhox Health costs $996/year for 4 tests ($249 per test).
Which tests more biomarkers, Blueprint or SiPhox Health?
Blueprint lists more biomarkers: 100+, compared with 59 for SiPhox Health. Of the markers in our database, 43 are in both panels.
Which gives more biomarkers per dollar, Blueprint or SiPhox Health?
Blueprint gives more biomarkers per dollar: 27.4 per $100 of annual cost, compared with 5.9 for SiPhox Health. Count alone does not decide it; check whether the markers you need are included.
What does Blueprint test that SiPhox Health doesn't?
73 markers in our database are in Blueprint's panel but not SiPhox Health's, including ABO Blood Type, Hematocrit, Red Blood Cell Count (RBC), and 70 more.
What does SiPhox Health test that Blueprint doesn't?
4 markers in our database are in SiPhox Health's panel but not Blueprint's, including TPO Antibodies (Thyroid Peroxidase), Thyroglobulin Antibodies, AMH (Anti-Mullerian Hormone), and 1 more.
How many tests per year do Blueprint and SiPhox Health include?
Blueprint includes 2 tests per year. SiPhox Health includes 4 tests per year.
Where do Blueprint and SiPhox Health draw blood?
Blueprint: Labcorp (3500+). SiPhox Health: At-home.
Can I use insurance with Blueprint or SiPhox Health?
Both are direct-to-consumer services paid out of pocket. Some buyers pay with HSA/FSA funds or submit receipts for out-of-network reimbursement; check with your plan and the provider.