Blueprint vs Healthspan
Complete Head-to-Head Comparison
Compare costs, biomarker coverage, and value to find the best blood testing service for your needs
Quick Comparison Summary
Best Value
Blueprint
27.4 biomarkers per $100
Most Comprehensive
Blueprint
100+ biomarkers tested
Most Tests Per Year
Tie
2 tests/year each
Cost & Value Comparison
Blueprint
Annual Cost$365
Tests per Year2
Total Biomarkers100+
Cost per Test$182
Healthspan
Annual Cost$1188
Tests per Year2
Total Biomarkers70+
Cost per Test$594
Service Details
| Feature | Blueprint | Healthspan |
|---|---|---|
| Lab Locations | Labcorp (3500+) | CLIA-certified labs |
| Key Features | Bryan Johnson protocol, Don't Die app results, personalized longevity protocols | Biological age calculation, rapamycin/acarbose/metformin protocols, GLP-1 protocols, longevity-focused panels |
| Notes | Restructured to a $365/year Biomarkers membership ($1/day, billed annually): two blood panels plus urine per year - a baseline of up to 140 biomarkers and a 6-month follow-up of up to 86, marketed as 100+ biomarkers and 160+ measurements per year. Labcorp partnership, 3,500+ US draw locations. One-time panels still sold separately: Basic $375 (67 biomarkers), Advanced $575 (108 biomarkers). Speed of Aging epigenetic test $325 and Microplastics test $135 are separate and not bundled. HSA/FSA eligible. | Model changed from a standalone $349 panel to a $99/month Longevity Optimization membership; the $1,188 shown is that rate annualized, not a figure Healthspan advertises. Core tier includes labs at baseline and 6 months (2/yr) tracking 70+ biomarkers across 9 biological systems; the Advanced tier runs labs quarterly but its price is not published. Includes BioAge+ biological age testing, 1:1 PhD-level coaching and clinician access. Treatment protocols priced separately ($25-$135/mo). Standalone panel pricing is no longer published publicly. Not to be confused with the unrelated myhealthspan.com. |
Biomarker Coverage Comparison
63
Tests in Common
53
Only in Blueprint
6
Only in Healthspan
Tests Only in Blueprint
- ABO Blood Type(Complete Blood Count (CBC))
- Magnesium(Electrolytes & Minerals)
- Total T4(Thyroid Function)
- Vitamin B12(Vitamins & Nutrients)
- Folate(Vitamins & Nutrients)
- Omega-3 Index / Fatty Acids(Advanced / Specialty Markers)
- Arachidonic Acid / EPA Ratio(Advanced / Specialty Markers)
- Heavy Metals - Lead(Advanced / Specialty Markers)
- Heavy Metals - Mercury(Advanced / Specialty Markers)
- ANA Titer(Autoimmune Markers)
- ANA Pattern(Autoimmune Markers)
- Rheumatoid Factor (RF)(Autoimmune Markers)
41 more
- PSA Free (Prostate Cancer)(Cancer Screening Markers)
- Mean Platelet Volume (MPV)(Complete Blood Count (CBC))
- Zinc(Electrolytes & Minerals)
- Lipase(Liver Function)
- Leptin(Advanced / Specialty Markers)
- Omega-6 Total(Advanced / Specialty Markers)
- Linoleic Acid(Advanced / Specialty Markers)
- Arachidonic Acid(Advanced / Specialty Markers)
- Non-HDL Cholesterol(Lipid Panel / Cardiovascular Health)
- Urine Appearance(Urinalysis)
- Urine Albumin(Urinalysis)
- Urine Color(Urinalysis)
- Urine pH(Urinalysis)
- Urine Specific Gravity(Urinalysis)
- Urine Protein(Urinalysis)
- Urine Glucose(Urinalysis)
- Urine Ketones(Urinalysis)
- Urine Bilirubin(Urinalysis)
- Urine Blood (Occult)(Urinalysis)
- Urine Nitrite(Urinalysis)
- Urine Leukocyte Esterase(Urinalysis)
- Urine WBC(Urinalysis)
- Urine RBC(Urinalysis)
- Urine Bacteria(Urinalysis)
- Squamous Epithelial Cells (Urine)(Urinalysis)
- Transitional Epithelial Cells (Urine)(Urinalysis)
- Renal Epithelial Cells (Urine)(Urinalysis)
- Hyaline Casts (Urine)(Urinalysis)
- Granular Casts (Urine)(Urinalysis)
- Urine Crystals(Urinalysis)
- Calcium Oxalate Crystals (Urine)(Urinalysis)
- Uric Acid Crystals (Urine)(Urinalysis)
- Triple Phosphate Crystals (Urine)(Urinalysis)
- Yeast (Urine)(Urinalysis)
- Reducing Substances (Urine)(Urinalysis)
- LDL Small(Lipid Panel / Cardiovascular Health)
- LDL Medium(Lipid Panel / Cardiovascular Health)
- LDL Pattern(Lipid Panel / Cardiovascular Health)
- LDL Peak Size(Lipid Panel / Cardiovascular Health)
- Omega-6/Omega-3 Ratio(Lipid Panel / Cardiovascular Health)
- Amylase(Pancreas & Digestive)
Tests Only in Healthspan
- LDL Particle Number(Lipid Panel / Cardiovascular Health)
- LDL Particle Size(Lipid Panel / Cardiovascular Health)
- AMH (Anti-Mullerian Hormone)(Sex Hormones (Female))
- ESR (Erythrocyte Sedimentation Rate)(Inflammation & Immune Markers)
- Neutrophil/Lymphocyte Ratio(Additional Specialized Tests)
- HDL Subfractions (Large/Small)(Additional Specialized Tests)
Full biomarker tableall 122 markers, side by side
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Frequently Asked Questions
Which is cheaper, Blueprint or Healthspan?
Blueprint is cheaper at $365/year, compared with $1,188/year for Healthspan.
How much do Blueprint and Healthspan cost per year?
Blueprint costs $365/year for 2 tests ($182 per test). Healthspan costs $1,188/year for 2 tests ($594 per test).
Which tests more biomarkers, Blueprint or Healthspan?
Blueprint lists more biomarkers: 100+, compared with 70+ for Healthspan. Of the markers in our database, 63 are in both panels.
Which gives more biomarkers per dollar, Blueprint or Healthspan?
Blueprint gives more biomarkers per dollar: 27.4 per $100 of annual cost, compared with 5.9 for Healthspan. Count alone does not decide it; check whether the markers you need are included.
What does Blueprint test that Healthspan doesn't?
53 markers in our database are in Blueprint's panel but not Healthspan's, including ABO Blood Type, Magnesium, Total T4, and 50 more.
What does Healthspan test that Blueprint doesn't?
6 markers in our database are in Healthspan's panel but not Blueprint's, including LDL Particle Number, LDL Particle Size, AMH (Anti-Mullerian Hormone), and 3 more.
How many tests per year do Blueprint and Healthspan include?
Blueprint includes 2 tests per year. Healthspan includes 2 tests per year.
Where do Blueprint and Healthspan draw blood?
Blueprint: Labcorp (3500+). Healthspan: CLIA-certified labs.
Can I use insurance with Blueprint or Healthspan?
Both are direct-to-consumer services paid out of pocket. Some buyers pay with HSA/FSA funds or submit receipts for out-of-network reimbursement; check with your plan and the provider.