Blueprint vs Empirical Health
Complete Head-to-Head Comparison
Compare costs, biomarker coverage, and value to find the best blood testing service for your needs
Quick Comparison Summary
Best Value
Empirical Health
52.6 biomarkers per $100
Most Comprehensive
Tie
100+ biomarkers each
Most Tests Per Year
Blueprint
2 tests/year
Cost & Value Comparison
Blueprint
Annual Cost$365
Tests per Year2
Total Biomarkers100+
Cost per Test$182
Empirical Health
Annual Cost$190
Tests per Year1
Total Biomarkers100+
Cost per Test$190
Service Details
| Feature | Blueprint | Empirical Health |
|---|---|---|
| Lab Locations | Labcorp (3500+) | 2200+ locations |
| Key Features | Bryan Johnson protocol, Don't Die app results, personalized longevity protocols | Personalized MD video visit included, doctor messaging, custom nutrition plan, exercise routines, mobile app |
| Notes | Restructured to a $365/year Biomarkers membership ($1/day, billed annually): two blood panels plus urine per year - a baseline of up to 140 biomarkers and a 6-month follow-up of up to 86, marketed as 100+ biomarkers and 160+ measurements per year. Labcorp partnership, 3,500+ US draw locations. One-time panels still sold separately: Basic $375 (67 biomarkers), Advanced $575 (108 biomarkers). Speed of Aging epigenetic test $325 and Microplastics test $135 are separate and not bundled. HSA/FSA eligible. | $190 per test with MD video visit included. Single lab visit. HSA/FSA eligible |
Biomarker Coverage Comparison
77
Tests in Common
39
Only in Blueprint
8
Only in Empirical Health
Tests Only in Blueprint
- ABO Blood Type(Complete Blood Count (CBC))
- GGT (Gamma-Glutamyl Transferase)(Liver Function)
- Free T3 (Triiodothyronine)(Thyroid Function)
- Total T4(Thyroid Function)
- Total Testosterone(Sex Hormones (Male))
- Free Testosterone(Sex Hormones (Male))
- SHBG (Sex Hormone Binding Globulin)(Sex Hormones (Male))
- PSA (Prostate Specific Antigen)(Sex Hormones (Male))
- DHEA-S(Sex Hormones (Male))
- Estradiol (E2)(Sex Hormones (Female))
- Progesterone(Sex Hormones (Female))
- FSH (Follicle Stimulating Hormone)(Sex Hormones (Female))
27 more
- LH (Luteinizing Hormone)(Sex Hormones (Female))
- Prolactin(Sex Hormones (Female))
- Homocysteine(Inflammation & Immune Markers)
- Cortisol(Stress & Adrenal Function)
- Omega-3 Index / Fatty Acids(Advanced / Specialty Markers)
- Arachidonic Acid / EPA Ratio(Advanced / Specialty Markers)
- Heavy Metals - Lead(Advanced / Specialty Markers)
- Heavy Metals - Mercury(Advanced / Specialty Markers)
- IGF-1 (Insulin-like Growth Factor)(Advanced / Specialty Markers)
- ANA Screen (Antinuclear Antibodies)(Autoimmune Markers)
- ANA Titer(Autoimmune Markers)
- ANA Pattern(Autoimmune Markers)
- Rheumatoid Factor (RF)(Autoimmune Markers)
- PSA Free (Prostate Cancer)(Cancer Screening Markers)
- Zinc(Electrolytes & Minerals)
- Lipase(Liver Function)
- Leptin(Advanced / Specialty Markers)
- Omega-6 Total(Advanced / Specialty Markers)
- Linoleic Acid(Advanced / Specialty Markers)
- Arachidonic Acid(Advanced / Specialty Markers)
- Urine Albumin(Urinalysis)
- LDL Small(Lipid Panel / Cardiovascular Health)
- LDL Medium(Lipid Panel / Cardiovascular Health)
- LDL Pattern(Lipid Panel / Cardiovascular Health)
- LDL Peak Size(Lipid Panel / Cardiovascular Health)
- Omega-6/Omega-3 Ratio(Lipid Panel / Cardiovascular Health)
- Amylase(Pancreas & Digestive)
Tests Only in Empirical Health
- Apolipoprotein A1 (ApoA1)(Lipid Panel / Cardiovascular Health)
- Total Cholesterol/HDL Ratio(Lipid Panel / Cardiovascular Health)
- LDL/HDL Ratio(Lipid Panel / Cardiovascular Health)
- ApoB/ApoA1 Ratio(Lipid Panel / Cardiovascular Health)
- De Ritis Ratio (AST/ALT)(Liver Function)
- Albumin/Globulin Ratio (A/G)(Kidney Function)
- Band Neutrophils(Complete Blood Count (CBC))
- Reactive Lymphocytes(Complete Blood Count (CBC))
Full biomarker tableall 124 markers, side by side
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Frequently Asked Questions
Which is cheaper, Blueprint or Empirical Health?
Empirical Health is cheaper at $190/year, compared with $365/year for Blueprint.
How much do Blueprint and Empirical Health cost per year?
Blueprint costs $365/year for 2 tests ($182 per test). Empirical Health costs $190/year for 1 test ($190 per test).
Which tests more biomarkers, Blueprint or Empirical Health?
Both list 100+ biomarkers. Of the markers in our database, 77 are in both panels.
Which gives more biomarkers per dollar, Blueprint or Empirical Health?
Empirical Health gives more biomarkers per dollar: 52.6 per $100 of annual cost, compared with 27.4 for Blueprint. Count alone does not decide it; check whether the markers you need are included.
What does Blueprint test that Empirical Health doesn't?
39 markers in our database are in Blueprint's panel but not Empirical Health's, including ABO Blood Type, GGT (Gamma-Glutamyl Transferase), Free T3 (Triiodothyronine), and 36 more.
What does Empirical Health test that Blueprint doesn't?
8 markers in our database are in Empirical Health's panel but not Blueprint's, including Apolipoprotein A1 (ApoA1), Total Cholesterol/HDL Ratio, LDL/HDL Ratio, and 5 more.
How many tests per year do Blueprint and Empirical Health include?
Blueprint includes 2 tests per year. Empirical Health includes 1 test per year.
Where do Blueprint and Empirical Health draw blood?
Blueprint: Labcorp (3500+). Empirical Health: 2200+ locations.
Can I use insurance with Blueprint or Empirical Health?
Both are direct-to-consumer services paid out of pocket. Some buyers pay with HSA/FSA funds or submit receipts for out-of-network reimbursement; check with your plan and the provider.