SiPhox Health vs Healthspan

Complete Head-to-Head Comparison

Compare costs, biomarker coverage, and value to find the best blood testing service for your needs

✓ Independent Analysis✓ Prices verified Aug 2026✓ Complete Biomarker Coverage

Quick Comparison Summary

Best Value
Healthspan
5.9 biomarkers per $100
Most Comprehensive
Healthspan
70+ biomarkers tested
Most Tests Per Year
SiPhox Health
4 tests/year

Cost & Value Comparison

Service Details

FeatureSiPhox HealthHealthspan
Lab LocationsAt-homeCLIA-certified labs
Key FeaturesNeedle-free EasyDraw device, AI longevity expert (Sai), wearable integrations (Oura/Fitbit/Apple Watch), supplement recommendations, third-party lab uploadsBiological age calculation, rapamycin/acarbose/metformin protocols, GLP-1 protocols, longevity-focused panels
NotesPriced here as the Ultimate 360 panel, the SKU the 59-biomarker count describes: membership $124 per test cycle plus the Ultimate 360 upgrade at +$125 per cycle, 4 quarterly cycles = $996/yr plus shipping. Membership alone is $124/cycle ($496/yr quarterly) and includes four switchable core panels: Longevity Essentials (25 biomarkers), Thyroid Focus, Hormone Focus, Heart & Metabolic. GLP Monitoring Panel +$75/cycle. At-home needle-free EasyDraw collection. Our 20% affiliate code applies to the first billing cycle only, membership only, excluding shipping and upgrades. HSA/FSA eligible.Model changed from a standalone $349 panel to a $99/month Longevity Optimization membership; the $1,188 shown is that rate annualized, not a figure Healthspan advertises. Core tier includes labs at baseline and 6 months (2/yr) tracking 70+ biomarkers across 9 biological systems; the Advanced tier runs labs quarterly but its price is not published. Includes BioAge+ biological age testing, 1:1 PhD-level coaching and clinician access. Treatment protocols priced separately ($25-$135/mo). Standalone panel pricing is no longer published publicly. Not to be confused with the unrelated myhealthspan.com.

Biomarker Coverage Comparison

42
Tests in Common
5
Only in SiPhox Health
27
Only in Healthspan

Tests Only in SiPhox Health

Tests Only in Healthspan

15 more
Full biomarker tableall 74 markers, side by side

Filter by Category

BiomarkerSiPhox HealthHealthspan
Complete Blood Count (CBC)
Hemoglobin✓✓
Hematocrit—✓
Red Blood Cell Count (RBC)—✓
White Blood Cell Count (WBC)—✓
Platelet Count—✓
MCV, MCH, MCHC—✓
RDW (Red Cell Distribution Width)—✓
Neutrophils—✓
Lymphocytes—✓
Monocytes—✓
Eosinophils—✓
Basophils—✓
Lipid Panel / Cardiovascular Health
Total Cholesterol✓✓
LDL Cholesterol✓✓
HDL Cholesterol✓✓
Triglycerides✓✓
VLDL Cholesterol✓✓
Apolipoprotein B (ApoB)✓✓
Lipoprotein (a)✓✓
LDL Particle Number—✓
LDL Particle Size—✓
Metabolic Health / Glucose
Fasting Glucose—✓
Hemoglobin A1c (HbA1c)✓✓
Insulin—✓
Uric Acid—✓
Liver Function
ALT (Alanine Aminotransferase)✓✓
AST (Aspartate Aminotransferase)✓✓
ALP (Alkaline Phosphatase)✓✓
GGT (Gamma-Glutamyl Transferase)—✓
Bilirubin (Total)✓✓
Albumin✓✓
Total Protein✓✓
Globulin✓✓
Kidney Function
Creatinine✓✓
BUN (Blood Urea Nitrogen)✓✓
eGFR (Estimated Glomerular Filtration Rate)✓✓
BUN/Creatinine Ratio✓✓
Electrolytes & Minerals
Sodium—✓
Potassium—✓
Chloride—✓
Carbon Dioxide (CO2)—✓
Calcium✓✓
Thyroid Function
TSH (Thyroid Stimulating Hormone)✓✓
Free T4 (Thyroxine)✓✓
Free T3 (Triiodothyronine)✓✓
TPO Antibodies (Thyroid Peroxidase)✓—
Thyroglobulin Antibodies✓—
Sex Hormones (Male)
Total Testosterone✓✓
Free Testosterone✓✓
SHBG (Sex Hormone Binding Globulin)✓✓
PSA (Prostate Specific Antigen)✓✓
DHEA-S✓✓
Sex Hormones (Female)
Estradiol (E2)✓✓
Progesterone✓✓
FSH (Follicle Stimulating Hormone)✓✓
LH (Luteinizing Hormone)✓✓
Prolactin✓✓
AMH (Anti-Mullerian Hormone)✓✓
Inflammation & Immune Markers
hs-CRP (High Sensitivity C-Reactive Protein)✓✓
ESR (Erythrocyte Sedimentation Rate)—✓
Homocysteine✓✓
Vitamins & Nutrients
Vitamin D (25-Hydroxy)✓✓
Vitamin B12✓—
Folate✓—
Ferritin✓✓
Iron (Serum)✓✓
TIBC (Total Iron Binding Capacity)—✓
Stress & Adrenal Function
Cortisol✓✓
Advanced / Specialty Markers
IGF-1 (Insulin-like Growth Factor)—✓
Autoimmune Markers
ANA Screen (Antinuclear Antibodies)—✓
Cancer Screening Markers
Additional Specialized Tests
Neutrophil/Lymphocyte Ratio—✓
HDL Subfractions (Large/Small)—✓
Transferrin Saturation✓✓
Free Androgen Index (FAI)✓—
Urinalysis
Pancreas & Digestive

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Frequently Asked Questions

Which is cheaper, SiPhox Health or Healthspan?
SiPhox Health is cheaper at $996/year, compared with $1,188/year for Healthspan.
How much do SiPhox Health and Healthspan cost per year?
SiPhox Health costs $996/year for 4 tests ($249 per test). Healthspan costs $1,188/year for 2 tests ($594 per test).
Which tests more biomarkers, SiPhox Health or Healthspan?
Healthspan lists more biomarkers: 70+, compared with 59 for SiPhox Health. Of the markers in our database, 42 are in both panels.
Which gives more biomarkers per dollar, SiPhox Health or Healthspan?
Both give 5.9 biomarkers per $100 of annual cost. Count alone does not decide it; check whether the markers you need are included.
What does SiPhox Health test that Healthspan doesn't?
5 markers in our database are in SiPhox Health's panel but not Healthspan's, including TPO Antibodies (Thyroid Peroxidase), Thyroglobulin Antibodies, Vitamin B12, and 2 more.
What does Healthspan test that SiPhox Health doesn't?
27 markers in our database are in Healthspan's panel but not SiPhox Health's, including Hematocrit, Red Blood Cell Count (RBC), White Blood Cell Count (WBC), and 24 more.
How many tests per year do SiPhox Health and Healthspan include?
SiPhox Health includes 4 tests per year. Healthspan includes 2 tests per year.
Where do SiPhox Health and Healthspan draw blood?
SiPhox Health: At-home. Healthspan: CLIA-certified labs.
Can I use insurance with SiPhox Health or Healthspan?
Both are direct-to-consumer services paid out of pocket. Some buyers pay with HSA/FSA funds or submit receipts for out-of-network reimbursement; check with your plan and the provider.

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