Empirical Health vs Healthspan
Complete Head-to-Head Comparison
Compare costs, biomarker coverage, and value to find the best blood testing service for your needs
Quick Comparison Summary
Best Value
Empirical Health
52.6 biomarkers per $100
Most Comprehensive
Empirical Health
100+ biomarkers tested
Most Tests Per Year
Healthspan
2 tests/year
Cost & Value Comparison
Empirical Health
Annual Cost$190
Tests per Year1
Total Biomarkers100+
Cost per Test$190
Healthspan
Annual Cost$1188
Tests per Year2
Total Biomarkers70+
Cost per Test$594
Service Details
| Feature | Empirical Health | Healthspan |
|---|---|---|
| Lab Locations | 2200+ locations | CLIA-certified labs |
| Key Features | Personalized MD video visit included, doctor messaging, custom nutrition plan, exercise routines, mobile app | Biological age calculation, rapamycin/acarbose/metformin protocols, GLP-1 protocols, longevity-focused panels |
| Notes | $190 per test with MD video visit included. Single lab visit. HSA/FSA eligible | Model changed from a standalone $349 panel to a $99/month Longevity Optimization membership; the $1,188 shown is that rate annualized, not a figure Healthspan advertises. Core tier includes labs at baseline and 6 months (2/yr) tracking 70+ biomarkers across 9 biological systems; the Advanced tier runs labs quarterly but its price is not published. Includes BioAge+ biological age testing, 1:1 PhD-level coaching and clinician access. Treatment protocols priced separately ($25-$135/mo). Standalone panel pricing is no longer published publicly. Not to be confused with the unrelated myhealthspan.com. |
Biomarker Coverage Comparison
47
Tests in Common
38
Only in Empirical Health
22
Only in Healthspan
Tests Only in Empirical Health
- Magnesium(Electrolytes & Minerals)
- Vitamin B12(Vitamins & Nutrients)
- Folate(Vitamins & Nutrients)
- Mean Platelet Volume (MPV)(Complete Blood Count (CBC))
- Apolipoprotein A1 (ApoA1)(Lipid Panel / Cardiovascular Health)
- Non-HDL Cholesterol(Lipid Panel / Cardiovascular Health)
- Total Cholesterol/HDL Ratio(Lipid Panel / Cardiovascular Health)
- LDL/HDL Ratio(Lipid Panel / Cardiovascular Health)
- ApoB/ApoA1 Ratio(Lipid Panel / Cardiovascular Health)
- De Ritis Ratio (AST/ALT)(Liver Function)
- Albumin/Globulin Ratio (A/G)(Kidney Function)
- Urine Appearance(Urinalysis)
26 more
- Urine Color(Urinalysis)
- Urine pH(Urinalysis)
- Urine Specific Gravity(Urinalysis)
- Urine Protein(Urinalysis)
- Urine Glucose(Urinalysis)
- Urine Ketones(Urinalysis)
- Urine Bilirubin(Urinalysis)
- Urine Blood (Occult)(Urinalysis)
- Urine Nitrite(Urinalysis)
- Urine Leukocyte Esterase(Urinalysis)
- Urine WBC(Urinalysis)
- Urine RBC(Urinalysis)
- Urine Bacteria(Urinalysis)
- Squamous Epithelial Cells (Urine)(Urinalysis)
- Transitional Epithelial Cells (Urine)(Urinalysis)
- Renal Epithelial Cells (Urine)(Urinalysis)
- Hyaline Casts (Urine)(Urinalysis)
- Granular Casts (Urine)(Urinalysis)
- Urine Crystals(Urinalysis)
- Calcium Oxalate Crystals (Urine)(Urinalysis)
- Uric Acid Crystals (Urine)(Urinalysis)
- Triple Phosphate Crystals (Urine)(Urinalysis)
- Yeast (Urine)(Urinalysis)
- Band Neutrophils(Complete Blood Count (CBC))
- Reactive Lymphocytes(Complete Blood Count (CBC))
- Reducing Substances (Urine)(Urinalysis)
Tests Only in Healthspan
- LDL Particle Number(Lipid Panel / Cardiovascular Health)
- LDL Particle Size(Lipid Panel / Cardiovascular Health)
- GGT (Gamma-Glutamyl Transferase)(Liver Function)
- Free T3 (Triiodothyronine)(Thyroid Function)
- Total Testosterone(Sex Hormones (Male))
- Free Testosterone(Sex Hormones (Male))
- SHBG (Sex Hormone Binding Globulin)(Sex Hormones (Male))
- PSA (Prostate Specific Antigen)(Sex Hormones (Male))
- DHEA-S(Sex Hormones (Male))
- Estradiol (E2)(Sex Hormones (Female))
- Progesterone(Sex Hormones (Female))
- FSH (Follicle Stimulating Hormone)(Sex Hormones (Female))
10 more
- LH (Luteinizing Hormone)(Sex Hormones (Female))
- Prolactin(Sex Hormones (Female))
- AMH (Anti-Mullerian Hormone)(Sex Hormones (Female))
- ESR (Erythrocyte Sedimentation Rate)(Inflammation & Immune Markers)
- Homocysteine(Inflammation & Immune Markers)
- Cortisol(Stress & Adrenal Function)
- IGF-1 (Insulin-like Growth Factor)(Advanced / Specialty Markers)
- ANA Screen (Antinuclear Antibodies)(Autoimmune Markers)
- Neutrophil/Lymphocyte Ratio(Additional Specialized Tests)
- HDL Subfractions (Large/Small)(Additional Specialized Tests)
Full biomarker tableall 107 markers, side by side
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Frequently Asked Questions
Which is cheaper, Empirical Health or Healthspan?
Empirical Health is cheaper at $190/year, compared with $1,188/year for Healthspan.
How much do Empirical Health and Healthspan cost per year?
Empirical Health costs $190/year for 1 test ($190 per test). Healthspan costs $1,188/year for 2 tests ($594 per test).
Which tests more biomarkers, Empirical Health or Healthspan?
Empirical Health lists more biomarkers: 100+, compared with 70+ for Healthspan. Of the markers in our database, 47 are in both panels.
Which gives more biomarkers per dollar, Empirical Health or Healthspan?
Empirical Health gives more biomarkers per dollar: 52.6 per $100 of annual cost, compared with 5.9 for Healthspan. Count alone does not decide it; check whether the markers you need are included.
What does Empirical Health test that Healthspan doesn't?
38 markers in our database are in Empirical Health's panel but not Healthspan's, including Magnesium, Vitamin B12, Folate, and 35 more.
What does Healthspan test that Empirical Health doesn't?
22 markers in our database are in Healthspan's panel but not Empirical Health's, including LDL Particle Number, LDL Particle Size, GGT (Gamma-Glutamyl Transferase), and 19 more.
How many tests per year do Empirical Health and Healthspan include?
Empirical Health includes 1 test per year. Healthspan includes 2 tests per year.
Where do Empirical Health and Healthspan draw blood?
Empirical Health: 2200+ locations. Healthspan: CLIA-certified labs.
Can I use insurance with Empirical Health or Healthspan?
Both are direct-to-consumer services paid out of pocket. Some buyers pay with HSA/FSA funds or submit receipts for out-of-network reimbursement; check with your plan and the provider.