Empirical Health vs SiPhox Health

Complete Head-to-Head Comparison

Compare costs, biomarker coverage, and value to find the best blood testing service for your needs

Empirical Health
✓ Independent Analysis✓ Prices verified Aug 2026✓ Complete Biomarker Coverage

Quick Comparison Summary

Best Value
Empirical Health
52.6 biomarkers per $100
Most Comprehensive
Empirical Health
100+ biomarkers tested
Most Tests Per Year
SiPhox Health
4 tests/year

Cost & Value Comparison

Service Details

FeatureEmpirical HealthSiPhox Health
Lab Locations2200+ locationsAt-home
Key FeaturesPersonalized MD video visit included, doctor messaging, custom nutrition plan, exercise routines, mobile appNeedle-free EasyDraw device, AI longevity expert (Sai), wearable integrations (Oura/Fitbit/Apple Watch), supplement recommendations, third-party lab uploads
Notes$190 per test with MD video visit included. Single lab visit. HSA/FSA eligiblePriced here as the Ultimate 360 panel, the SKU the 59-biomarker count describes: membership $124 per test cycle plus the Ultimate 360 upgrade at +$125 per cycle, 4 quarterly cycles = $996/yr plus shipping. Membership alone is $124/cycle ($496/yr quarterly) and includes four switchable core panels: Longevity Essentials (25 biomarkers), Thyroid Focus, Hormone Focus, Heart & Metabolic. GLP Monitoring Panel +$75/cycle. At-home needle-free EasyDraw collection. Our 20% affiliate code applies to the first billing cycle only, membership only, excluding shipping and upgrades. HSA/FSA eligible.

Biomarker Coverage Comparison

30
Tests in Common
55
Only in Empirical Health
17
Only in SiPhox Health

Tests Only in Empirical Health

43 more

Tests Only in SiPhox Health

5 more
Full biomarker tableall 102 markers, side by side

Filter by Category

BiomarkerEmpirical HealthSiPhox Health
Complete Blood Count (CBC)
Hemoglobin✓✓
Hematocrit✓—
Red Blood Cell Count (RBC)✓—
White Blood Cell Count (WBC)✓—
Platelet Count✓—
MCV, MCH, MCHC✓—
RDW (Red Cell Distribution Width)✓—
Mean Platelet Volume (MPV)✓—
Neutrophils✓—
Lymphocytes✓—
Monocytes✓—
Eosinophils✓—
Basophils✓—
Band Neutrophils✓—
Reactive Lymphocytes✓—
Lipid Panel / Cardiovascular Health
Total Cholesterol✓✓
LDL Cholesterol✓✓
HDL Cholesterol✓✓
Triglycerides✓✓
VLDL Cholesterol✓✓
Apolipoprotein B (ApoB)✓✓
Lipoprotein (a)✓✓
Apolipoprotein A1 (ApoA1)✓—
Non-HDL Cholesterol✓—
Total Cholesterol/HDL Ratio✓—
LDL/HDL Ratio✓—
ApoB/ApoA1 Ratio✓—
Metabolic Health / Glucose
Fasting Glucose✓—
Hemoglobin A1c (HbA1c)✓✓
Insulin✓—
Uric Acid✓—
Liver Function
ALT (Alanine Aminotransferase)✓✓
AST (Aspartate Aminotransferase)✓✓
ALP (Alkaline Phosphatase)✓✓
Bilirubin (Total)✓✓
Albumin✓✓
Total Protein✓✓
Globulin✓✓
De Ritis Ratio (AST/ALT)✓—
Kidney Function
Creatinine✓✓
BUN (Blood Urea Nitrogen)✓✓
eGFR (Estimated Glomerular Filtration Rate)✓✓
BUN/Creatinine Ratio✓✓
Albumin/Globulin Ratio (A/G)✓—
Electrolytes & Minerals
Sodium✓—
Potassium✓—
Chloride✓—
Carbon Dioxide (CO2)✓—
Calcium✓✓
Magnesium✓—
Thyroid Function
TSH (Thyroid Stimulating Hormone)✓✓
Free T4 (Thyroxine)✓✓
Free T3 (Triiodothyronine)—✓
TPO Antibodies (Thyroid Peroxidase)—✓
Thyroglobulin Antibodies—✓
Sex Hormones (Male)
Total Testosterone—✓
Free Testosterone—✓
SHBG (Sex Hormone Binding Globulin)—✓
PSA (Prostate Specific Antigen)—✓
DHEA-S—✓
Sex Hormones (Female)
Estradiol (E2)—✓
Progesterone—✓
FSH (Follicle Stimulating Hormone)—✓
LH (Luteinizing Hormone)—✓
Prolactin—✓
AMH (Anti-Mullerian Hormone)—✓
Inflammation & Immune Markers
hs-CRP (High Sensitivity C-Reactive Protein)✓✓
Homocysteine—✓
Vitamins & Nutrients
Vitamin D (25-Hydroxy)✓✓
Vitamin B12✓✓
Folate✓✓
Ferritin✓✓
Iron (Serum)✓✓
TIBC (Total Iron Binding Capacity)✓—
Stress & Adrenal Function
Cortisol—✓
Advanced / Specialty Markers
Autoimmune Markers
Cancer Screening Markers
Additional Specialized Tests
Transferrin Saturation✓✓
Free Androgen Index (FAI)—✓
Urinalysis
Urine Appearance✓—
Urine Color✓—
Urine pH✓—
Urine Specific Gravity✓—
Urine Protein✓—
Urine Glucose✓—
Urine Ketones✓—
Urine Bilirubin✓—
Urine Blood (Occult)✓—
Urine Nitrite✓—
Urine Leukocyte Esterase✓—
Urine WBC✓—
Urine RBC✓—
Urine Bacteria✓—
Squamous Epithelial Cells (Urine)✓—
Transitional Epithelial Cells (Urine)✓—
Renal Epithelial Cells (Urine)✓—
Hyaline Casts (Urine)✓—
Granular Casts (Urine)✓—
Urine Crystals✓—
Calcium Oxalate Crystals (Urine)✓—
Uric Acid Crystals (Urine)✓—
Triple Phosphate Crystals (Urine)✓—
Yeast (Urine)✓—
Reducing Substances (Urine)✓—
Pancreas & Digestive

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Frequently Asked Questions

Which is cheaper, Empirical Health or SiPhox Health?
Empirical Health is cheaper at $190/year, compared with $996/year for SiPhox Health.
How much do Empirical Health and SiPhox Health cost per year?
Empirical Health costs $190/year for 1 test ($190 per test). SiPhox Health costs $996/year for 4 tests ($249 per test).
Which tests more biomarkers, Empirical Health or SiPhox Health?
Empirical Health lists more biomarkers: 100+, compared with 59 for SiPhox Health. Of the markers in our database, 30 are in both panels.
Which gives more biomarkers per dollar, Empirical Health or SiPhox Health?
Empirical Health gives more biomarkers per dollar: 52.6 per $100 of annual cost, compared with 5.9 for SiPhox Health. Count alone does not decide it; check whether the markers you need are included.
What does Empirical Health test that SiPhox Health doesn't?
55 markers in our database are in Empirical Health's panel but not SiPhox Health's, including Hematocrit, Red Blood Cell Count (RBC), White Blood Cell Count (WBC), and 52 more.
What does SiPhox Health test that Empirical Health doesn't?
17 markers in our database are in SiPhox Health's panel but not Empirical Health's, including Free T3 (Triiodothyronine), TPO Antibodies (Thyroid Peroxidase), Thyroglobulin Antibodies, and 14 more.
How many tests per year do Empirical Health and SiPhox Health include?
Empirical Health includes 1 test per year. SiPhox Health includes 4 tests per year.
Where do Empirical Health and SiPhox Health draw blood?
Empirical Health: 2200+ locations. SiPhox Health: At-home.
Can I use insurance with Empirical Health or SiPhox Health?
Both are direct-to-consumer services paid out of pocket. Some buyers pay with HSA/FSA funds or submit receipts for out-of-network reimbursement; check with your plan and the provider.

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