Blueprint Advanced vs Healthspan

Complete Head-to-Head Comparison

Compare costs, biomarker coverage, and value to find the best blood testing service for your needs

Blueprint Advanced
Healthspan
Independent Analysis 2025 Updated Pricing Complete Biomarker Coverage

Quick Comparison Summary

Best Value
Healthspan
22.9 biomarkers per $100
Most Comprehensive
Blueprint Advanced
110 biomarkers tested
Most Tests Per Year
Blueprint Advanced
2 tests/year

Cost & Value Comparison

Service Details

FeatureBlueprint AdvancedHealthspan
Lab Locations3500+ LabcorpQuest/Labcorp
Key FeaturesBryan Johnson protocol, toxic exposure testing, fast resultsBiological age calculation, rapamycin/acarbose protocol support, longevity-focused panels
NotesBasic panel $750/yr (67 markers). Soon FSA/HSA eligibleLongevity Pro $349 (80+ biomarkers), Starter $55. Labs included with treatment protocols. HSA/FSA eligible

Biomarker Coverage Comparison

60
Tests in Common
6
Only in Blueprint Advanced
12
Only in Healthspan

Tests Only in Blueprint Advanced

Tests Only in Healthspan

Complete Biomarker Comparison by Category

BiomarkerBlueprint AdvancedHealthspan
Complete Blood Count (CBC)
Hemoglobin
Hematocrit
Red Blood Cell Count (RBC)
White Blood Cell Count (WBC)
Platelet Count
MCV, MCH, MCHC
RDW (Red Cell Distribution Width)
Neutrophils
Lymphocytes
Monocytes
Eosinophils
Basophils
Lipid Panel / Cardiovascular Health
Total Cholesterol
LDL Cholesterol
HDL Cholesterol
Triglycerides
VLDL Cholesterol
Apolipoprotein B (ApoB)
Lipoprotein (a)
LDL Particle Number
LDL Particle Size
Metabolic Health / Glucose
Fasting Glucose
Hemoglobin A1c (HbA1c)
Insulin
Uric Acid
Liver Function
ALT (Alanine Aminotransferase)
AST (Aspartate Aminotransferase)
ALP (Alkaline Phosphatase)
GGT (Gamma-Glutamyl Transferase)
Bilirubin (Total)
Albumin
Total Protein
Globulin
Kidney Function
Creatinine
BUN (Blood Urea Nitrogen)
eGFR (Estimated Glomerular Filtration Rate)
BUN/Creatinine Ratio
Electrolytes &Minerals
Sodium
Potassium
Chloride
Carbon Dioxide (CO2)
Calcium
Magnesium
Thyroid Function
TSH (Thyroid Stimulating Hormone)
Free T4 (Thyroxine)
Free T3 (Triiodothyronine)
Total T4
Sex Hormones (Male)
Total Testosterone
Free Testosterone
SHBG (Sex Hormone Binding Globulin)
Estradiol (E2)
PSA (Prostate Specific Antigen)
DHEA-S
Sex Hormones (Female)
Estradiol (E2)
Progesterone
FSH (Follicle Stimulating Hormone)
LH (Luteinizing Hormone)
Prolactin
AMH (Anti-Mullerian Hormone)
Inflammation &Immune Markers
hs-CRP (High Sensitivity C-Reactive Protein)
ESR (Erythrocyte Sedimentation Rate)
Homocysteine
Vitamins &Nutrients
Vitamin D (25-Hydroxy)
Vitamin B12
Folate
Ferritin
Iron (Serum)
TIBC (Total Iron Binding Capacity)
Stress &Adrenal Function
Cortisol
Advanced / Specialty Markers
Heavy Metals - Lead
Heavy Metals - Mercury
IGF-1 (Insulin-like Growth Factor)
Autoimmune Markers
ANA Screen (Antinuclear Antibodies)
Cancer Screening Markers
Additional Specialized Tests
Neutrophil/Lymphocyte Ratio
LDL-P (LDL Particle Number)
LDL Particle Size Analysis
HDL Subfractions (Large/Small)
Transferrin Saturation
Urinalysis

Ready to Choose?

Based on this comparison, make an informed decision about your blood testing provider

Frequently Asked Questions

Which provider is better:Blueprint Advanced or Healthspan?
Healthspan provides better value with 22.9 biomarkers per $100 spent, offering more comprehensive coverage for your investment. However, the best choice depends on your specific health goals, budget, and which biomarkers are most important for your situation.
How much do Blueprint Advanced and Healthspan cost per year?
Blueprint Advanced costs $1150 per year for 2, while Healthspan costs $349 per year for 1. The cost per test is $575 for Blueprint Advanced and $349 for Healthspan.
What biomarkers does Blueprint Advanced test that Healthspan doesn't?
Blueprint Advanced includes 6 unique biomarkers not found in Healthspan's panel. These include Magnesium, Total T4, Vitamin B12, and others.
Can I use insurance with Blueprint Advanced or Healthspan?
Both Blueprint Advanced and Healthspan are direct-to-consumer services that typically don't accept insurance. However, you may be able to submit receipts to your insurance for reimbursement if you have out-of-network benefits, or use HSA/FSA funds for payment. Check with your insurance provider and the testing companies for specific policies.
How often should I get blood work done?
Most health optimization experts recommend testing 2-4 times per year to establish baselines and track trends. Blueprint Advanced includes 2 in their annual membership, while Healthspan includes 1. More frequent testing allows you to track the effectiveness of interventions and catch changes early.
Where can I get blood drawn for these tests?
Blueprint Advanced uses 3500+ Labcorp, while Healthspan uses Quest/Labcorp. Both typically have thousands of collection centers nationwide. You'll schedule your blood draw through their platform after ordering.

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