Empirical Health vs Vitality Blueprint Standard

Complete Head-to-Head Comparison

Compare costs, biomarker coverage, and value to find the best blood testing service for your needs

Empirical Health
Vitality Blueprint Standard
✓ Independent Analysis✓ Prices verified Aug 2026✓ Complete Biomarker Coverage

Quick Comparison Summary

Best Value
Empirical Health
52.6 biomarkers per $100
Most Comprehensive
Vitality Blueprint Standard
108 biomarkers tested
Most Tests Per Year
Tie
1 tests/year each

Cost & Value Comparison

Service Details

FeatureEmpirical HealthVitality Blueprint Standard
Lab Locations2200+ locationsUS/Canada nationwide
Key FeaturesPersonalized MD video visit included, doctor messaging, custom nutrition plan, exercise routines, mobile appAndy Galpin co-founded, performance reference ranges, 13-week optimization cycles, 80 biomarker patterns
Notes$190 per test with MD video visit included. Single lab visit. HSA/FSA eligibleStarting at $375/year membership, or $425 for a single cycle. 108 biomarkers analyzed across 9 Functional Areas and 20+ systemic constraints. Vitality Score plus a personalized 13-week protocol covering nutrition, supplements, training and behavior. Retesting recommended quarterly at discounted member rates. US and Canada.

Biomarker Coverage Comparison

46
Tests in Common
39
Only in Empirical Health
16
Only in Vitality Blueprint Standard

Tests Only in Empirical Health

27 more

Tests Only in Vitality Blueprint Standard

4 more
Full biomarker tableall 101 markers, side by side

Filter by Category

BiomarkerEmpirical HealthVitality Blueprint Standard
Complete Blood Count (CBC)
Hemoglobin✓✓
Hematocrit✓✓
Red Blood Cell Count (RBC)✓✓
White Blood Cell Count (WBC)✓✓
Platelet Count✓✓
MCV, MCH, MCHC✓✓
RDW (Red Cell Distribution Width)✓✓
Mean Platelet Volume (MPV)✓✓
Immature Granulocytes—✓
nRBC (Nucleated Red Blood Cells)—✓
Neutrophils✓✓
Lymphocytes✓✓
Monocytes✓✓
Eosinophils✓✓
Basophils✓✓
Band Neutrophils✓—
Reactive Lymphocytes✓—
Lipid Panel / Cardiovascular Health
Total Cholesterol✓✓
LDL Cholesterol✓✓
HDL Cholesterol✓✓
Triglycerides✓✓
VLDL Cholesterol✓✓
Apolipoprotein B (ApoB)✓—
Lipoprotein (a)✓—
Apolipoprotein A1 (ApoA1)✓—
Non-HDL Cholesterol✓—
Total Cholesterol/HDL Ratio✓—
LDL/HDL Ratio✓—
ApoB/ApoA1 Ratio✓—
Metabolic Health / Glucose
Fasting Glucose✓✓
Hemoglobin A1c (HbA1c)✓✓
Insulin✓—
Uric Acid✓—
Liver Function
ALT (Alanine Aminotransferase)✓✓
AST (Aspartate Aminotransferase)✓✓
ALP (Alkaline Phosphatase)✓✓
GGT (Gamma-Glutamyl Transferase)—✓
Bilirubin (Total)✓✓
Albumin✓✓
Total Protein✓✓
Globulin✓✓
De Ritis Ratio (AST/ALT)✓—
Kidney Function
Creatinine✓✓
BUN (Blood Urea Nitrogen)✓✓
eGFR (Estimated Glomerular Filtration Rate)✓✓
BUN/Creatinine Ratio✓✓
Albumin/Globulin Ratio (A/G)✓—
Electrolytes & Minerals
Sodium✓✓
Potassium✓✓
Chloride✓✓
Carbon Dioxide (CO2)✓✓
Calcium✓✓
Magnesium✓✓
Thyroid Function
TSH (Thyroid Stimulating Hormone)✓✓
Free T4 (Thyroxine)✓✓
Free T3 (Triiodothyronine)—✓
Sex Hormones (Male)
Total Testosterone—✓
Free Testosterone—✓
SHBG (Sex Hormone Binding Globulin)—✓
DHEA-S—✓
Sex Hormones (Female)
Estradiol (E2)—✓
FSH (Follicle Stimulating Hormone)—✓
LH (Luteinizing Hormone)—✓
Inflammation & Immune Markers
hs-CRP (High Sensitivity C-Reactive Protein)✓✓
ESR (Erythrocyte Sedimentation Rate)—✓
Homocysteine—✓
Ferritin/CRP Ratio—✓
Vitamins & Nutrients
Vitamin D (25-Hydroxy)✓—
Vitamin B12✓✓
Folate✓✓
Ferritin✓✓
Iron (Serum)✓✓
TIBC (Total Iron Binding Capacity)✓✓
UIBC (Unsaturated Iron Binding Capacity)—✓
Stress & Adrenal Function
Cortisol—✓
Advanced / Specialty Markers
Autoimmune Markers
Cancer Screening Markers
Additional Specialized Tests
Transferrin Saturation✓✓
Urinalysis
Urine Appearance✓—
Urine Color✓—
Urine pH✓—
Urine Specific Gravity✓—
Urine Protein✓—
Urine Glucose✓—
Urine Ketones✓—
Urine Bilirubin✓—
Urine Blood (Occult)✓—
Urine Nitrite✓—
Urine Leukocyte Esterase✓—
Urine WBC✓—
Urine RBC✓—
Urine Bacteria✓—
Squamous Epithelial Cells (Urine)✓—
Transitional Epithelial Cells (Urine)✓—
Renal Epithelial Cells (Urine)✓—
Hyaline Casts (Urine)✓—
Granular Casts (Urine)✓—
Urine Crystals✓—
Calcium Oxalate Crystals (Urine)✓—
Uric Acid Crystals (Urine)✓—
Triple Phosphate Crystals (Urine)✓—
Yeast (Urine)✓—
Reducing Substances (Urine)✓—
Pancreas & Digestive

Ready to Choose?

Based on this comparison, make an informed decision about your blood testing provider

Frequently Asked Questions

Which is cheaper, Empirical Health or Vitality Blueprint Standard?
Empirical Health is cheaper at $190/year, compared with $375/year for Vitality Blueprint Standard.
How much do Empirical Health and Vitality Blueprint Standard cost per year?
Empirical Health costs $190/year for 1 test ($190 per test). Vitality Blueprint Standard costs $375/year for 1 test ($375 per test).
Which tests more biomarkers, Empirical Health or Vitality Blueprint Standard?
Vitality Blueprint Standard lists more biomarkers: 108, compared with 100+ for Empirical Health. Of the markers in our database, 46 are in both panels.
Which gives more biomarkers per dollar, Empirical Health or Vitality Blueprint Standard?
Empirical Health gives more biomarkers per dollar: 52.6 per $100 of annual cost, compared with 28.8 for Vitality Blueprint Standard. Count alone does not decide it; check whether the markers you need are included.
What does Empirical Health test that Vitality Blueprint Standard doesn't?
39 markers in our database are in Empirical Health's panel but not Vitality Blueprint Standard's, including Apolipoprotein B (ApoB), Lipoprotein (a), Insulin, and 36 more.
What does Vitality Blueprint Standard test that Empirical Health doesn't?
16 markers in our database are in Vitality Blueprint Standard's panel but not Empirical Health's, including GGT (Gamma-Glutamyl Transferase), Free T3 (Triiodothyronine), Total Testosterone, and 13 more.
How many tests per year do Empirical Health and Vitality Blueprint Standard include?
Empirical Health includes 1 test per year. Vitality Blueprint Standard includes 1 test per year.
Where do Empirical Health and Vitality Blueprint Standard draw blood?
Empirical Health: 2200+ locations. Vitality Blueprint Standard: US/Canada nationwide.
Can I use insurance with Empirical Health or Vitality Blueprint Standard?
Both are direct-to-consumer services paid out of pocket. Some buyers pay with HSA/FSA funds or submit receipts for out-of-network reimbursement; check with your plan and the provider.

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