Blueprint Advanced vs Empirical Health

Complete Head-to-Head Comparison

Compare costs, biomarker coverage, and value to find the best blood testing service for your needs

Blueprint Advanced
Empirical Health
Independent Analysis 2025 Updated Pricing Complete Biomarker Coverage

Quick Comparison Summary

Best Value
Empirical Health
44.7 biomarkers per $100
Most Comprehensive
Blueprint Advanced
110 biomarkers tested
Most Tests Per Year
Blueprint Advanced
2 tests/year

Cost & Value Comparison

Service Details

FeatureBlueprint AdvancedEmpirical Health
Lab Locations3500+ Labcorp2200+ locations
Key FeaturesBryan Johnson protocol, toxic exposure testing, fast resultsPersonalized MD video visit included, doctor messaging, custom nutrition plan, exercise routines, mobile app
NotesBasic panel $750/yr (67 markers). Soon FSA/HSA eligible$190 per test with MD review included. Best value with physician consultation. Single lab visit. HSA/FSA eligible

Biomarker Coverage Comparison

49
Tests in Common
17
Only in Blueprint Advanced
36
Only in Empirical Health

Tests Only in Blueprint Advanced

Tests Only in Empirical Health

Complete Biomarker Comparison by Category

BiomarkerBlueprint AdvancedEmpirical Health
Complete Blood Count (CBC)
Hemoglobin
Hematocrit
Red Blood Cell Count (RBC)
White Blood Cell Count (WBC)
Platelet Count
MCV, MCH, MCHC
RDW (Red Cell Distribution Width)
Mean Platelet Volume (MPV)
Neutrophils
Lymphocytes
Monocytes
Eosinophils
Basophils
Band Neutrophils
Reactive Lymphocytes
Lipid Panel / Cardiovascular Health
Total Cholesterol
LDL Cholesterol
HDL Cholesterol
Triglycerides
VLDL Cholesterol
Apolipoprotein B (ApoB)
Lipoprotein (a)
Apolipoprotein A1 (ApoA1)
Non-HDL Cholesterol
Total Cholesterol/HDL Ratio
LDL/HDL Ratio
ApoB/ApoA1 Ratio
Metabolic Health / Glucose
Fasting Glucose
Hemoglobin A1c (HbA1c)
Insulin
Uric Acid
Liver Function
ALT (Alanine Aminotransferase)
AST (Aspartate Aminotransferase)
ALP (Alkaline Phosphatase)
GGT (Gamma-Glutamyl Transferase)
Bilirubin (Total)
Albumin
Total Protein
Globulin
De Ritis Ratio (AST/ALT)
Kidney Function
Creatinine
BUN (Blood Urea Nitrogen)
eGFR (Estimated Glomerular Filtration Rate)
BUN/Creatinine Ratio
Albumin/Globulin Ratio (A/G)
Electrolytes &Minerals
Sodium
Potassium
Chloride
Carbon Dioxide (CO2)
Calcium
Magnesium
Thyroid Function
TSH (Thyroid Stimulating Hormone)
Free T4 (Thyroxine)
Free T3 (Triiodothyronine)
Total T4
Sex Hormones (Male)
Total Testosterone
Free Testosterone
SHBG (Sex Hormone Binding Globulin)
Estradiol (E2)
PSA (Prostate Specific Antigen)
DHEA-S
Sex Hormones (Female)
Estradiol (E2)
Progesterone
FSH (Follicle Stimulating Hormone)
LH (Luteinizing Hormone)
Inflammation &Immune Markers
hs-CRP (High Sensitivity C-Reactive Protein)
Homocysteine
Vitamins &Nutrients
Vitamin D (25-Hydroxy)
Vitamin B12
Folate
Ferritin
Iron (Serum)
TIBC (Total Iron Binding Capacity)
Stress &Adrenal Function
Cortisol
Advanced / Specialty Markers
Heavy Metals - Lead
Heavy Metals - Mercury
Autoimmune Markers
Cancer Screening Markers
Additional Specialized Tests
Transferrin Saturation
Urinalysis
Urine Appearance
Urine Color
Urine pH
Urine Specific Gravity
Urine Protein
Urine Glucose
Urine Ketones
Urine Bilirubin
Urine Blood (Occult)
Urine Nitrite
Urine Leukocyte Esterase
Urine WBC
Urine RBC
Urine Bacteria
Squamous Epithelial Cells (Urine)
Transitional Epithelial Cells (Urine)
Renal Epithelial Cells (Urine)
Hyaline Casts (Urine)
Granular Casts (Urine)
Urine Crystals
Calcium Oxalate Crystals (Urine)
Uric Acid Crystals (Urine)
Triple Phosphate Crystals (Urine)
Yeast (Urine)
Reducing Substances (Urine)

Ready to Choose?

Based on this comparison, make an informed decision about your blood testing provider

Frequently Asked Questions

Which provider is better:Blueprint Advanced or Empirical Health?
Empirical Health provides better value with 44.7 biomarkers per $100 spent, offering more comprehensive coverage for your investment. However, the best choice depends on your specific health goals, budget, and which biomarkers are most important for your situation.
How much do Blueprint Advanced and Empirical Health cost per year?
Blueprint Advanced costs $1150 per year for 2, while Empirical Health costs $190 per year for 1. The cost per test is $575 for Blueprint Advanced and $190 for Empirical Health.
What biomarkers does Blueprint Advanced test that Empirical Health doesn't?
Blueprint Advanced includes 17 unique biomarkers not found in Empirical Health's panel. These include GGT (Gamma-Glutamyl Transferase), Free T3 (Triiodothyronine), Total T4, and others.
Can I use insurance with Blueprint Advanced or Empirical Health?
Both Blueprint Advanced and Empirical Health are direct-to-consumer services that typically don't accept insurance. However, you may be able to submit receipts to your insurance for reimbursement if you have out-of-network benefits, or use HSA/FSA funds for payment. Check with your insurance provider and the testing companies for specific policies.
How often should I get blood work done?
Most health optimization experts recommend testing 2-4 times per year to establish baselines and track trends. Blueprint Advanced includes 2 in their annual membership, while Empirical Health includes 1. More frequent testing allows you to track the effectiveness of interventions and catch changes early.
Where can I get blood drawn for these tests?
Blueprint Advanced uses 3500+ Labcorp, while Empirical Health uses 2200+ locations. Both typically have thousands of collection centers nationwide. You'll schedule your blood draw through their platform after ordering.

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