Blueprint Advanced vs SiPhox Health

Complete Head-to-Head Comparison

Compare costs, biomarker coverage, and value to find the best blood testing service for your needs

Blueprint Advanced
SiPhox Health
Independent Analysis 2025 Updated Pricing Complete Biomarker Coverage

Quick Comparison Summary

Best Value
SiPhox Health
48.0 biomarkers per $100
Most Comprehensive
Blueprint Advanced
110 biomarkers tested
Most Tests Per Year
SiPhox Health
4 tests/year

Cost & Value Comparison

Service Details

FeatureBlueprint AdvancedSiPhox Health
Lab Locations3500+ LabcorpAt-home
Key FeaturesBryan Johnson protocol, toxic exposure testing, fast resultsNeedle-free EasyDraw device, AI longevity expert, wearable integrations (Oura/Whoop/Apple Watch), supplement recommendations
NotesBasic panel $750/yr (67 markers). Soon FSA/HSA eligible$125/test. Ultimate 360 panel has 60 biomarkers. Results in 5-7 days. HSA/FSA eligible

Biomarker Coverage Comparison

42
Tests in Common
24
Only in Blueprint Advanced
6
Only in SiPhox Health

Tests Only in Blueprint Advanced

Tests Only in SiPhox Health

Complete Biomarker Comparison by Category

BiomarkerBlueprint AdvancedSiPhox Health
Complete Blood Count (CBC)
Hemoglobin
Hematocrit
Red Blood Cell Count (RBC)
White Blood Cell Count (WBC)
Platelet Count
MCV, MCH, MCHC
RDW (Red Cell Distribution Width)
Neutrophils
Lymphocytes
Monocytes
Eosinophils
Basophils
Lipid Panel / Cardiovascular Health
Total Cholesterol
LDL Cholesterol
HDL Cholesterol
Triglycerides
VLDL Cholesterol
Apolipoprotein B (ApoB)
Lipoprotein (a)
Metabolic Health / Glucose
Fasting Glucose
Hemoglobin A1c (HbA1c)
Insulin
Uric Acid
Liver Function
ALT (Alanine Aminotransferase)
AST (Aspartate Aminotransferase)
ALP (Alkaline Phosphatase)
GGT (Gamma-Glutamyl Transferase)
Bilirubin (Total)
Albumin
Total Protein
Globulin
Kidney Function
Creatinine
BUN (Blood Urea Nitrogen)
eGFR (Estimated Glomerular Filtration Rate)
BUN/Creatinine Ratio
Electrolytes &Minerals
Sodium
Potassium
Chloride
Carbon Dioxide (CO2)
Calcium
Magnesium
Thyroid Function
TSH (Thyroid Stimulating Hormone)
Free T4 (Thyroxine)
Free T3 (Triiodothyronine)
TPO Antibodies (Thyroid Peroxidase)
Thyroglobulin Antibodies
Total T4
Sex Hormones (Male)
Total Testosterone
Free Testosterone
SHBG (Sex Hormone Binding Globulin)
Estradiol (E2)
PSA (Prostate Specific Antigen)
DHEA-S
Sex Hormones (Female)
Estradiol (E2)
Progesterone
FSH (Follicle Stimulating Hormone)
LH (Luteinizing Hormone)
Prolactin
AMH (Anti-Mullerian Hormone)
Inflammation &Immune Markers
hs-CRP (High Sensitivity C-Reactive Protein)
Homocysteine
Vitamins &Nutrients
Vitamin D (25-Hydroxy)
Vitamin B12
Folate
Ferritin
Iron (Serum)
TIBC (Total Iron Binding Capacity)
Stress &Adrenal Function
Cortisol
Advanced / Specialty Markers
Heavy Metals - Lead
Heavy Metals - Mercury
Autoimmune Markers
Cancer Screening Markers
Additional Specialized Tests
Transferrin Saturation
Free Androgen Index (FAI)
Urinalysis

Ready to Choose?

Based on this comparison, make an informed decision about your blood testing provider

Frequently Asked Questions

Which provider is better:Blueprint Advanced or SiPhox Health?
SiPhox Health provides better value with 48.0 biomarkers per $100 spent, offering more comprehensive coverage for your investment. However, the best choice depends on your specific health goals, budget, and which biomarkers are most important for your situation.
How much do Blueprint Advanced and SiPhox Health cost per year?
Blueprint Advanced costs $1150 per year for 2, while SiPhox Health costs $125 per year for 4. The cost per test is $575 for Blueprint Advanced and $31 for SiPhox Health.
What biomarkers does Blueprint Advanced test that SiPhox Health doesn't?
Blueprint Advanced includes 24 unique biomarkers not found in SiPhox Health's panel. These include Hematocrit, Red Blood Cell Count (RBC), White Blood Cell Count (WBC), and others.
Can I use insurance with Blueprint Advanced or SiPhox Health?
Both Blueprint Advanced and SiPhox Health are direct-to-consumer services that typically don't accept insurance. However, you may be able to submit receipts to your insurance for reimbursement if you have out-of-network benefits, or use HSA/FSA funds for payment. Check with your insurance provider and the testing companies for specific policies.
How often should I get blood work done?
Most health optimization experts recommend testing 2-4 times per year to establish baselines and track trends. Blueprint Advanced includes 2 in their annual membership, while SiPhox Health includes 4. More frequent testing allows you to track the effectiveness of interventions and catch changes early.
Where can I get blood drawn for these tests?
Blueprint Advanced uses 3500+ Labcorp, while SiPhox Health uses At-home. Both typically have thousands of collection centers nationwide. You'll schedule your blood draw through their platform after ordering.

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