Life Extension vs Blueprint Advanced

Cost & Value Comparison

Life Extension

Annual Cost: $486

Tests per Year: 2

Total Biomarkers: 40+

Cost per Test: $243.00

Blueprint Advanced

Annual Cost: $1150

Tests per Year: 2

Total Biomarkers: 110

Cost per Test: $575.00

Service Details

Feature	Life Extension	Blueprint Advanced
Lab Locations	Quest locations	3500+ Labcorp
Key Features	Male/Female panels, free wellness specialist consultation	Bryan Johnson protocol, toxic exposure testing, fast results
Notes	Annual sale pricing $243/test. Added cortisol in 2025. HSA/FSA eligible	Basic panel $750/yr (67 markers). Soon FSA/HSA eligible

Biomarker Coverage Comparison

Tests in common: 47 biomarkers

Only in Life Extension: 0 biomarkers

Only in Blueprint Advanced: 14 biomarkers

Tests Only in Blueprint Advanced

Lipoprotein (a) (Lipid Panel / Cardiovascular Health)
GGT (Gamma-Glutamyl Transferase) (Liver Function)
BUN/Creatinine Ratio (Kidney Function)
Free T3 (Triiodothyronine) (Thyroid Function)
Total T4 (Thyroid Function)
SHBG (Sex Hormone Binding Globulin) (Sex Hormones (Male))
FSH (Follicle Stimulating Hormone) (Sex Hormones (Female))
LH (Luteinizing Hormone) (Sex Hormones (Female))
Vitamin B12 (Vitamins &Nutrients)
Folate (Vitamins &Nutrients)
Iron (Serum) (Vitamins &Nutrients)
TIBC (Total Iron Binding Capacity) (Vitamins &Nutrients)
Heavy Metals - Lead (Advanced / Specialty Markers)
Heavy Metals - Mercury (Advanced / Specialty Markers)

Complete Biomarker Comparison by Category

Biomarker	Life Extension	Blueprint Advanced
Complete Blood Count (CBC)
Hemoglobin	✓	✓
Hematocrit	✓	✓
Red Blood Cell Count (RBC)	✓	✓
White Blood Cell Count (WBC)	✓	✓
Platelet Count	✓	✓
MCV, MCH, MCHC	✓	✓
RDW (Red Cell Distribution Width)	✓	✓
Lipid Panel / Cardiovascular Health
Total Cholesterol	✓	✓
LDL Cholesterol	✓	✓
HDL Cholesterol	✓	✓
Triglycerides	✓	✓
VLDL Cholesterol	✓	✓
Apolipoprotein B (ApoB)	✓	✓
Lipoprotein (a)	—	✓
Metabolic Health / Glucose
Fasting Glucose	✓	✓
Hemoglobin A1c (HbA1c)	✓	✓
Insulin	✓	✓
Uric Acid	✓	✓
Liver Function
ALT (Alanine Aminotransferase)	✓	✓
AST (Aspartate Aminotransferase)	✓	✓
ALP (Alkaline Phosphatase)	✓	✓
GGT (Gamma-Glutamyl Transferase)	—	✓
Bilirubin (Total)	✓	✓
Albumin	✓	✓
Total Protein	✓	✓
Globulin	✓	✓
Kidney Function
Creatinine	✓	✓
BUN (Blood Urea Nitrogen)	✓	✓
eGFR (Estimated Glomerular Filtration Rate)	✓	✓
BUN/Creatinine Ratio	—	✓
Electrolytes &Minerals
Sodium	✓	✓
Potassium	✓	✓
Chloride	✓	✓
Carbon Dioxide (CO2)	✓	✓
Calcium	✓	✓
Magnesium	✓	✓
Thyroid Function
TSH (Thyroid Stimulating Hormone)	✓	✓
Free T4 (Thyroxine)	✓	✓
Free T3 (Triiodothyronine)	—	✓
Total T4	—	✓
Sex Hormones (Male)
Total Testosterone	✓	✓
Free Testosterone	✓	✓
SHBG (Sex Hormone Binding Globulin)	—	✓
Estradiol (E2)	✓	✓
PSA (Prostate Specific Antigen)	✓	✓
DHEA-S	✓	✓
Sex Hormones (Female)
Estradiol (E2)	✓	✓
Progesterone	✓	✓
FSH (Follicle Stimulating Hormone)	—	✓
LH (Luteinizing Hormone)	—	✓
Inflammation &Immune Markers
hs-CRP (High Sensitivity C-Reactive Protein)	✓	✓
Homocysteine	✓	✓
Vitamins &Nutrients
Vitamin D (25-Hydroxy)	✓	✓
Vitamin B12	—	✓
Folate	—	✓
Ferritin	✓	✓
Iron (Serum)	—	✓
TIBC (Total Iron Binding Capacity)	—	✓
Stress &Adrenal Function
Cortisol	✓	✓
Advanced / Specialty Markers
Heavy Metals - Lead	—	✓
Heavy Metals - Mercury	—	✓
Autoimmune Markers
Cancer Screening Markers
Additional Specialized Tests