Signos vs Zoe

CGM Head-to-Head Comparison

Compare pricing, sensor technology, app features, and coaching support to find the best CGM for your goals

Signos
$139/mo
Signos
Zoe
$29/mo
Zoe
✓ Independent Analysis✓ November 2025 Pricing✓ Feature-by-Feature Comparison

Quick Comparison Summary

Best Value
Zoe
Lower monthly cost
Best Accuracy
Signos
Lower MARD%
Best Support
Signos
Better coaching
Longest Wear Time
Signos
Longer sensor life

Pricing & Plans Comparison

Signos

Monthly Cost$139
Annual Cost$834
Sensors IncludedYes (2/month)
Min. Commitment3 months

Zoe

Monthly Cost$29
Annual Cost$642
Sensors IncludedNo (gut test only)
Min. Commitment4 months

Sensor Technology

SpecificationSignosZoe
Sensor TypeDexcom SteloN/A - no CGM
Accuracy (MARD)8.3%N/A
Reading FrequencyEvery 5 minN/A
Warm-up Time30 minN/A
Wear Time15 daysN/A
Water Resistance8ft/24hrN/A

App Features & Coaching

FeatureSignosZoe
Coaching TypeAI coachingPersonalized nutrition AI
Food LoggingPhoto + manual loggingPhoto + manual + barcode scanning
Scoring SystemWeight loss score + meal scoresZOE score (0-100) per food
App IntegrationsApple Health, Apple WatchApple Health
Prescription RequiredNot requiredNot required
HSA/FSA Eligible✓ Yes✓ Yes

Key Features

Signos

Best for: Weight loss

Key features: Real-time glucose tracking, AI meal insights, exercise recommendations, weight loss tools, GLP-1 integration support

Not recommended for: Insulin users, active cancer treatment, eating disorders

Zoe

Best for: Gut health + nutrition

Key features: Gut microbiome analysis, blood fat testing, AI meal recommendations, food scoring

Not recommended for: Those wanting CGM tracking

Signos Details

FDA-cleared for weight management (Aug 2025). Uses Dexcom Stelo sensors. 3-month ($139/mo) or 6-month ($129/mo) plans.

Zoe Details

US:$294 test kit (gut + blood) + $29-39/mo. Sept 2025 update:simplified test no longer includes CGM. UK-based.

Ready to Choose?

Based on this comparison, select the CGM service that best fits your health goals

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Frequently Asked Questions

Which is better:Signos or Zoe?
Signos is best for weight loss, while Zoe is ideal for gut health + nutrition. Zoe is more affordable at $29/month compared to Signos's $139/month. The best choice depends on your specific health goals and budget.
How much do Signos and Zoe cost?
Signos costs $139/month ($834/year), while Zoe costs $29/month ($642/year). Both services are HSA/FSA eligible.
Which CGM sensor is more accurate?
Signos uses Dexcom Stelo with 8.3% MARD, while Zoe uses N/A - no CGM with N/A MARD. Lower MARD indicates better accuracy. Both are considered highly accurate for wellness purposes.
Do I need a prescription for Signos or Zoe?
Neither Signos nor Zoe requires a prescription. Both are available over-the-counter or include telehealth consultations.
Which has better coaching support?
Signos offers AI coaching, while Zoe provides Personalized nutrition AI.
Can I use Signos or Zoe for weight loss?
Signos is specifically designed for weight loss. CGMs help identify which foods spike your blood sugar, enabling dietary changes that support weight loss without medication.

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