Osteocalcin
Osteocalcin is a noncollagenous protein made by osteoblasts during bone formation and is released into blood as a marker of bone turnover. Elevated levels occur during rapid bone growth, fracture healing, and high-turnover conditions such as hyperparathyroidism, while low levels suggest reduced bone formation. Its undercarboxylated form has also been linked to glucose metabolism.
Optimal range: who says what
No institution or named practitioner we track states an optimal target for Osteocalcin. How we verify ranges.
- General guidance, no named sourceWithin referenceNo separate optimal established. Reflects bone turnover and vitamin K status
- Lab reference interval9-42 ng/mLWhat a lab report flags against. A lab interval is not an optimal target.
1 providers include this
Advanced / Specialty Markers
Why Osteocalcin matters
Indicates rate of bone formation. Low levels suggest poor bone building. Also affects glucose metabolism and testosterone. Marker for osteoporosis treatment effectiveness.
Which Providers Test Osteocalcin?
Of the panels we itemize, only Function Health ($365/year, 160+ biomarkers) includes Osteocalcin.
1 panel that includes it, cheapest first
| Provider | Annual Cost | Total Biomarkers | $/Biomarker |
|---|---|---|---|
 Function Health | $365 | 160+ | $2.28 |
$/Biomarker is annual cost divided by the panel's advertised biomarker count, not the price of this one test. We track 23 blood test providers (32 plans); 21 of those plans are itemized marker by marker. Compare all of them.
20 itemized panels do not include Osteocalcin
Superpower · WHOOP Advanced Labs · Labcorp OnDemand · Life Extension Elite · Everlywell · Mito Health · InsideTracker · Marek Health Base · Marek Health Comprehensive · Marek Health Complete · Marek Health Executive · Blueprint · Empirical Health · Oura Health Panels · SiPhox Health · Hims Labs · Healthspan · Vitality Blueprint Standard · Vitality Blueprint Elite · Ultrahuman Blood Vision Annual
11 providers not itemized in our matrix
We have not itemized these marker by marker (some sell tests one at a time), so this page cannot say whether they offer Osteocalcin. Check with them directly.
Life Extension Standard · Quest Health · Ultrahuman Blood Vision · Lifeforce · Hundred Health · Personalabs · Walk-In Lab · HealthLabs · WHOOP Specialized Panels · Marek Health Essential · Vitality Blueprint Upload
Frequently Asked Questions
What is the optimal range for Osteocalcin?
No institution or named practitioner we track states an optimal target for Osteocalcin. General guidance without a named source: Within reference (No separate optimal established). Lab reference interval: 9-42 ng/mL. That is what a lab report flags against, not an optimal target.
Which blood test providers include Osteocalcin?
1 of the 21 blood testing panels we itemize marker by marker include Osteocalcin in their panels. This biomarker has limited availability.
Medical Disclaimer
This information is for educational purposes only and is not medical advice. Always consult with a qualified healthcare provider about your specific health needs.
Last reviewed Aug 26, 2026 · First published Nov 30, 2025