Lp-PLA2 (PLAC Test)
Lp-PLA2 is a vascular-specific inflammatory enzyme bound mostly to LDL and associated with rupture-prone arterial plaque. Elevated activity or mass levels approximately double the risk of coronary events and ischemic stroke. Unlike hs-CRP, Lp-PLA2 reflects inflammation inside the artery wall rather than systemic inflammation and may guide risk stratification.
Optimal range: who says what
Institutions, researchers and practitioners draw the line in different places. Each position is listed with who holds it and, where a document states it, a link. How we verify ranges.
- Institution or study<200 ng/mLPLAC test risk cutoff2008 consensus panel cutoff for the mass assay; activity assays use different units and thresholds
- Lab reference interval<200 ng/mLWhat a lab report flags against. A lab interval is not an optimal target.
1 providers include this
Lipid Panel / Cardiovascular Health
Why Lp-PLA2 (PLAC Test) matters
Indicates unstable, rupture-prone arterial plaque. Elevated levels double stroke and coronary heart disease risk. Specific marker for vascular inflammation inside artery walls.
Which Providers Test Lp-PLA2 (PLAC Test)?
Of the panels we itemize, only Marek Health Executive ($1950/year, 130+ biomarkers) includes Lp-PLA2 (PLAC Test).
1 panel that includes it, cheapest first
| Provider | Annual Cost | Total Biomarkers | $/Biomarker |
|---|---|---|---|
| $1950 | 130+ | $15.00 |
$/Biomarker is annual cost divided by the panel's advertised biomarker count, not the price of this one test. We track 23 blood test providers (32 plans); 21 of those plans are itemized marker by marker. Compare all of them.
20 itemized panels do not include Lp-PLA2 (PLAC Test)
Superpower · WHOOP Advanced Labs · Labcorp OnDemand · Life Extension Elite · Everlywell · Mito Health · InsideTracker · Function Health · Marek Health Base · Marek Health Comprehensive · Marek Health Complete · Blueprint · Empirical Health · Oura Health Panels · SiPhox Health · Hims Labs · Healthspan · Vitality Blueprint Standard · Vitality Blueprint Elite · Ultrahuman Blood Vision Annual
11 providers not itemized in our matrix
We have not itemized these marker by marker (some sell tests one at a time), so this page cannot say whether they offer Lp-PLA2 (PLAC Test). Check with them directly.
Life Extension Standard · Quest Health · Ultrahuman Blood Vision · Lifeforce · Hundred Health · Personalabs · Walk-In Lab · HealthLabs · WHOOP Specialized Panels · Marek Health Essential · Vitality Blueprint Upload
Frequently Asked Questions
What is the optimal range for Lp-PLA2 (PLAC Test)?
Published position: <200 ng/mL (PLAC test risk cutoff). Lab reference interval: <200 ng/mL. That is what a lab report flags against, not an optimal target.
Which blood test providers include Lp-PLA2 (PLAC Test)?
1 of the 21 blood testing panels we itemize marker by marker include Lp-PLA2 (PLAC Test) in their panels. This biomarker has limited availability.
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Medical Disclaimer
This information is for educational purposes only and is not medical advice. Always consult with a qualified healthcare provider about your specific health needs.
Last reviewed Sep 3, 2026 · First published Nov 30, 2025